STAPHYLOCOCCI ISOLATED FROM PYODERMAS AND THEIR SENSITIVITIES TO ANTIBIOTICS

Onimura

1982

Self Cite

We investigated coagulase types by a simplified method for coagulase typing and antibiotic sensitivities by a disk diffusion method in 557 strains of Staphylococcus aureus isolated from lesions of vatious bacterial skin infections. Every strain investigated fell into only one of eight coagulase types by coagulase typing, and obvious correlations were seen between the coagulase types and the antibiograms. It was suggested that compatibility-incompatibility relationships might be present between genes of coagulases of different coagulase types and antibiotic resistance plasmids.

Section: Discussionmentioning

confidence: 99%

“…·Present address: Department of Dermatology, Shimane MedicalUniversity, 89-1 Enya-cho, Izumo693,japan. fections, typing them by coagulase typing and determining their antibiotic sensitivities by the disk diffusion method were as described previously (3,4), with slight modifications.…”

Section: Methodsmentioning

confidence: 99%

CORRELATIONS BETWEEN COAGULASE TYPES AND ANTIBIOGRAMS OF STAPHYLOCOCCUS AUREUS FROM BACTERIAL SKIN INFECTIONS

Onimura

1982

Self Cite

“…Isolation of Staphylococci from the lesions, and examinations of their abilities to utilize mannitol and to produce lipase and their sensitivities to antibiotics were carried out as previously described (11), with slight modifications. Gram-positive cocci isolated from the lesions were streaked on mannitol salt agar plates (Eiken Chemical Co., Tokyo) containing 5-10% chicken egg yolk, and they were incubated at 37°C for 24 hrs, If the bacteria grew, they were classified as Staphylococci.…”

Section: Methodsmentioning

confidence: 99%

COAGULASE TYPES OF COAGULASE‐POSITIVE STAPHYLOCOCCI FROM BACTERIAL SKIN INFECTIONS

Onimura

1981

Self Cite

Coagulase types of the strains of coagulase‐positive Staphylococci isolated from bacterial skin infections were determined by the simplified method for coagulase typing. The abilities to utilize mannitol and to produce lipase and the sensitivities to antibiotics were also examined. Relationships were obvious between the coagulase types and the other characters as well as the studied dermatoses. Coagulase typing is considered to be a suitable method for the classification of coagulase‐positive Staphylococci in studies of staphylococcal skin infections, because the procedure is relatively simple, all strains of coagulase‐positive Staphylococci were classifiable in this study, and the results were useful for understanding staphylococcal skin infections.

“…Although it is well known that a furuncle is usually caused by Staphylococcus aureus (1), the precise mechanisms by which the bacteria originate the disease remain unknown. It is not yet understood why many more bacteria than those inoculated under natural conditions are necessary to produce a furuncle experimentally in normal human volunteers (2).…”

Section: Introductionmentioning

confidence: 99%

PROMOTION OF COAGULASE RELEASE BY SERUM ALBUMIN IN SAPHYLOCOCCUS AUREUS DERIVED FROM FURUNCLE

Jidoi

1984

Self Cite

Three strains of Staphylococcus aureus derived from furuncles were cultured in media with and without bovine serum albumin, and coagulase titers in the media were examined. Although the titers were increased during the early to mid log phases of growth and decreased after the mid log phase in the medium without serum albumin, they were increased both during the early to mid log phase, and after the mid log phase as well in the medium with serum albumin. As coagulase probably protects the bacteria from the natural defense mechanisms of the host, these results suggest that Staphylococcus aureus introduced to damaged skin surfaces with accumulated plasma‐like fluid proliferates well because of the prolonged high coagulase level around them, allowing the number of bacteria to become great enough to produce a furuncle.