“…To date, up to 17 different mutations of the SLURP‐1 gene have been described in relation to MDM phenotypes . The c.82delT mutation, found in our patient, was previously reported in several ethnicities with high rates of consanguinity (Tunisian, Algerian, Italian, Scottish, and Croatian) and seems to be the most common mutation in the Mediterranean population indicating a founder effect of Mediterranean origins . Melanoma can arise during hereditary PPK (Papillon–Lefevre syndrome, Nagashima‐type palmoplantar keratosis, Greither's disease) .…”