SECTION OF BIOLOGY: SYMPOSIUM ON SITOSTEROL I. THE EFFECTS OF SITOSTEROL INGESTION ON SERUM CHOLESTEROL CONCENTRATION*

Trends in Drug Therapy†

“…In the area of cardiovascular drugs the problem of atherosclerosis in coronary disease, the use of vasopressors to control hypotensive shock accompanying myocardial infarction, and the development of potent hypotensive agents for the management of severe hypertension are attracting major attention. Oral administration of a soya extract of sitosterols (Cytellin) to increase the excretion of cholesterol and combat hypercholesterolemia is proposed for adjunctive use in controlling the intake of dietary fat as another means of discouraging the progression of atherosclerosis (7). The cerebroside fraction of a mammalian brain extract also has been found to be active orally in reducing the serum cholesterol level in patients with coronary disease.…”

“…Oral administration of a soya extract of sitosterols (Cytellin) to increase the excretion of cholesterol and combat hypercholesterolemia is proposed for adjunctive use Vol. V in controlling the intake of dietary fat as another means of discouraging the progression of atherosclerosis (7). The cerebroside fraction of a mammalian brain extract also has been found to be active orally in reducing the serum cholesterol level in patients with coronary disease.…”