Sarcoptes scabiei in Infundibulum of Nodular Scabies

Nodular scabies versus postscabies prurigo: a critical review of the literature

“…9 Postscabietic nodules are caused by a delayed, chronic hypersensitivity reaction to antigens of the mite. 10,15,18,19,21,22 The diagnosis of postscabietic nodules is possible when: a) there is a history of scabies which had been successfully treated; b) reddish-brown, large, round, papulonodular lesions are present (also in non typical locations for scabies). In the previously cited Indian study, scrotum (96.5% of patients) and penis (69%) were the commonest affected sites, followed by axillae (37.9%) and groins (17.2%); 9 c) patients complain of severe pruritus; d) microscopical, histopathological and dermoscopic examinations are negative for mites or parts of them, eggs and scybala; e) specific anti-scabies therapy is ineffective and f) the disease may persist for weeks or months.…”

“…3,5,9,15 Recovery is possible by means of potent topical 15,27 or intralesional corticosteroids. 4,15,19,27 Pimecrolimus 17 and tacrolimus 25,27 are also sometimes effective. Cryotherapy 29 and surgical excision 4 have also been used.…”

Treatment of postscabies prurigo with diflucortolone and chlorquinaldol in a group of African refugees

“…3 PSP is caused by a delayed, chronic hypersensitivity reaction to unknown antigens of the mite. [4][5][6][7][8][9] The diagnosis of PSP requires all the following criteria to be present: (2) a history of scabies which has been successfully treated; (2) round, reddish-brown, papulo-nodular lesions (also in un-typical locations of scabies); (3) complaints of severe itching; (4) absence of mites or parts thereof, eggs and scybala on microscopic, dermatoscopic and histopathologic examinations; (5) ineffective specific anti-scabies therapy; and (6) persistence of the disease for weeks or months. 5 PSP is more frequent in men 3,4 and children.…”

“…3,5,6,10,11 Recovery may occur with the use of potent topical or intralesional corticosteroids. 5,7,12,13 Pimecrolimus 14 and tacrolimus 12,15 are sometimes effective. Cryotherapy 16 and surgical excision 13 have also been used.…”

“…3 PSP is caused by a delayed, chronic hypersensitivity reaction to unknown antigens of the mite. 4–9…”