Retracted: COVID‐19 mortality and its predictors in the elderly: A systematic review

Abstract

Background and Aims: Older people have higher rates of comorbidities and may experience more severe inflammatory responses; therefore, are at higher risk of death. Herein, we aimed to systematically review the mortality in coronavirus disease 2019 (COVID-19) patients and its predictors in this age group.Methods: We searched PubMed, Web of Science, and Science Direct using relevant keywords. Retrieved records underwent a two-step screening process consisting of title/abstract and full-text screenings to identify the eligible studies.Results: Summarizing findings of 35 studies demonstrated that older patients have higher mortality rates compared to the younger population. A review of articles revealed that increasing age, body mass index, a male gender, dementia, impairment or dependency in daily activities, presence of consolidations on chest X-ray, hypoxemic respiratory failure, and lower oxygen saturation at admission were risk factors for death. High D-dimer levels, 25-hydroxy vitamin D serum deficiencies, high C-reactive protein (≥5 mg/L) levels plus any other abnormalities of lymphocyte,

Validation of the T-Lymphocyte Subset Index (TLSI) as a Score to Predict Mortality in Unvaccinated Hospitalized COVID-19 Patients

“…In this study, as widely demonstrated in the literature, older age, the presence of at least one comorbidity, and male sex were confirmed as risk factors associated with increased COVID-19 mortality [ 12 , 13 ]. In our cohort, among the collected comorbidities, cardiovascular, cerebrovascular, chronic pulmonary, renal, and hematologic diseases and solid organ tumors were significantly associated with increased mortality.…”

Risk Factors and Mortality in Elderly ARDS COVID-19 Compared to Patients without COVID-19

“…In the largest cohort of hospitalized patients with COVID-19, the increased age was an independent risk factor for mortality, with odds risk approximately doubling for an age between 65 and 79 years compared to 50 and 64 years [ 19 ]. A systematic review showed that mortality from COVID-19 was independently associated with the patient’s age and older patients were more likely to be admitted to intensive care and develop ARDS [ 20 ]. Patients aged 70 years represented up to 28 of the total COVID-19 critically ill patients admitted to intensive care [ 21 ].…”

C-Reactive protein role in assessing COVID-19 deceased geriatrics and survivors of severe and critical illness

“…Aging increases inflammatory responses to pathogens and reduces the efficacy of suppressing infections. A positive correlation was confirmed between older ages and increased mortality rates (MR); sixty-year-old patients had mortality rates of 4.5% vs 1.4% for patients under sixty years[ 3 , 4 ]. Recinella et al [ 5 ] study declared a one-and-a-half-fold increase in MR for every five years of a patient's age.…”