<i>Rasayana</i> in perspective of the present scenario

Goyal, Mandip

doi:10.4103/ayu.ayu_300_18

Cited by 20 publications

(8 citation statements)

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“…Rasayans can be defined as rejuvenating formulations that help to maintain good health, increase healthy life-span and even restore youth [ 22 ]. Some rasayans are also designed as remedies for specific disorders, but even these perform the promotive functions (in addition to disease amelioration) mentioned above.…”

Section: Use Of Lipids In Ayurvedic Therapeuticsmentioning

confidence: 99%

Ayurvedic lipid based rasayans - A perspective on the preparation and pharmacological significance of lipids on the bioavailability of phytoconstituents

Bali

Prasad

Saini

2022

Journal of Ayurveda and Integrative Medicine

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For thousands of years, lipid based Ayurvedic formulations have been made in India, and the craft has survived down the millennia up to the present time. Some of these deliciously potent phytonutrient preparations are very popular and have sustained the test of time pertaining to their efficacy. Recent researches on the role of phytonutrients in promoting cardio-pulmonary, brain and immune health substantially buttress the philosophy underlying the use of lipids in preparing these emulsions, since a large number of these bioactives are lipophilic. Being lipoidic, they are absorbed through the lacteals in the small intestine, and are then transported through the thoracic duct directly to the heart, bypassing the liver. The formulations utilizing ghee (clarified butter) or sesame oil as the carrier lipid, either while frying the myrobalams or as Anupana (adjuvant), have special significance in modulating bodily immunity, since the immune system is housed in lymphatics which are lipid rich. Amla and lipid based Ayurvedic rasayans (rejuvenating formulations) are a popular and highly palatable group of phytonutraceutical preparations. This group of polyherbal adaptogenic formulations is classified separately from other formulations in Ayurvedic therapeutics. Several of these health-promoting rasayans are suitable to be consumed by all age-groups in the recommended season and dose. Current research on endothelial and immune cell receptor mediated uptake of lipoidic molecules, together with the knowledge of lipid absorption pathways, lends credence to the usefulness of rasayans in targeting the cardio-pulmonary and immune systems. An attempt has been made in this paper to elucidate the mechanisms underpinning the complex interplay between lipid delivered hydrophobic phyto-molecules, systemic lymphatics and the Immune system.

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Section: Use Of Lipids In Ayurvedic Therapeuticsmentioning

confidence: 99%

Ayurvedic lipid based rasayans - A perspective on the preparation and pharmacological significance of lipids on the bioavailability of phytoconstituents

Bali

Prasad

Saini

2022

Journal of Ayurveda and Integrative Medicine

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“…This aligns with the previous study on Rasayana in the present scenario. 20 Most of the Rasayanas mentioned by the respondents were specifically mentioned in disease like Shvasa, Kasa, most probably because of the involvement of Prana Vayu, Uras, and Siras in the Sthanasamsraya and further pathogenesis of such diseases. In line with the management of respiratory viral infections, the respondents proposed almost similar line of treatment in COVID-19 treatment, i.e., by adopting the line of treatment of Jvara, Shvasa, Kasa, Agnideepana, Krimihara, and Vishahara along with principles of Nidana Parivarjana (disease prevention), Janapadadvamsa (epidemic management), and immunomodulation (Fig.…”

Section: Discussionmentioning

confidence: 99%

A Cross-sectional Study on Knowledge, Attitude, and Practice among Ayurveda Fraternity in the Management of Viral Infections of Respiratory Tract w.s.r. to Pranavaha Sroto Vikara on the Backdrop of COVID-19 Pandemic

Jameela¹,

Rao²,

Rao³

et al. 2020

Journal of Research in Ayurvedic Sciences

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The world has been witnessing threats due to different types of viral infections of respiratory system like the recent coronavirus disease-2019 (COVID-19) pandemic. Unfortunately, the conventional system of medicine has not come up with a successful strategy for the management of cases or for effective prevention. The development of a successful drug or novel vaccine is imperative at this stage of the outbreak and numerous research activities are underway. Ayurveda has legacy in the prevention and management of different types of diseases including viral infections, but with little documented evidence. In this study, Ayurveda physicians knowledge, attitude, and practice (KAP) toward the management of viral respiratory infections using a self-developed online KAP questionnaire having 28 questions was assessed. Six hundred and three Ayurveda physicians all over India across different affiliation and practice settings participated in the survey with a 65% response rate. Majority of respondents (73.4%) manage different types of viral infections and 85.3% positively responded to the involvement of gastrointestinal (GI) symptoms in viral respiratory infections. Nearly all the participants (98%) confirm the involvement of Pranavaha Srotas in the pathogenesis and 73% confirm the role of Agni also. The viral respiratory infections of respiratory tract are correlated mainly to Jvara, Shvasa, Kasa, and Agantu Roga. 79.43% physicians positively responded to the involvement of diet and regimens in the management of viral diseases. Sixty-six percent of the respondents manage such infections in line of Jvara, while 96.28% recommends that there is a definite role of Rasayana drugs and formulations in the management. Among the line of treatment suggested in the management of COVID-19 like illness, Jvarahara, and immune-modulation were the most recommended ones. Ayurveda manages various novel infections by its customized strategies ranging from prevention and therapeutic intervention. Ayurveda uses different seasonal and daily regimens; Rasayanas, suitable Shamana, and Shodhana interventions are selected based on different assessments to evaluate various aspects of disease and specific attributes of the patient. Systematic documentation and evidence generation may shed light on the importance of Ayurveda in combating novel infections of the present and future.

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“…According to new evidence, possible mechanisms include immunostimulation, tempering free radicals, boosting cellular detoxification mechanisms, repairing damaged non-proliferating cells, initiating cell proliferation and self-renewal of deteriorated proliferating tissues, and regenerating them by replacing damaged or deformed cells with fresh cells. [16] The word Rasayana is made up of two words 'Rasa' and 'Ayana', which refers to a method of obtaining good quality Rasa in the body for circulation. The status of this Rasa in the body has a direct impact on an individual's health, hence achieving the highest level of Rasa is known as Rasayana.…”

Section: Concept Of Rasayanamentioning

confidence: 99%

Immunotherapeutic Effect of Rasayanas in Cancer: A Conceptual Study

Datta

Jayanthi

Patil³

2022

Int J Ayu Pharm Res

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The natural repertory of the normal human immune system’s NK and T cells, as well as pharmacological elaborations, includes killing tumour cells. Aggressive human malignancies, on the other hand, are selected by the host immune system’s death of sensitive tumour cells and the survival of immune-resistant cancer cells. The capacity of these cells to evade “normal” immune killing actions could be a primary cause of malignancy progression, resulting in clonal growth, metastases, and patient death. The Ayurvedic idea of Vyadhikshamatwa, (Immunity) which re-engages the immune system to stage a counter-revolution, lays the path for a considerable clinical improvement in overall survival of patients with enhanced quality of life. Strategies like Rasayana Chikitsa can help to boost attempts to remove immune suppression in tumours by rousing dormant T-cell activity and restoring immune surveillance, especially when combined with chemotherapy and radiotherapy. The study uncovers aspects of cancer, immunotherapy, Ayurvedic aspects of Immunity and evidence of Immunotherapeutic properties of Rasayanas. Immunostimulatory immunotherapy, such as Rasayana Chikitsa, is the focus of this work which could show to be highly effective by restoring the patient’s inherent immune powers, opening up a new therapeutic front in the clinical arena of Cancer. Although the clinical studies are limited, the present study hope towards more approvals and wider usage of Rasayana Chikitsa in Cancer.

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Rasayana in perspective of the present scenario

Cited by 20 publications

References 0 publications

Ayurvedic lipid based rasayans - A perspective on the preparation and pharmacological significance of lipids on the bioavailability of phytoconstituents

Ayurvedic lipid based rasayans - A perspective on the preparation and pharmacological significance of lipids on the bioavailability of phytoconstituents

A Cross-sectional Study on Knowledge, Attitude, and Practice among Ayurveda Fraternity in the Management of Viral Infections of Respiratory Tract w.s.r. to Pranavaha Sroto Vikara on the Backdrop of COVID-19 Pandemic

Immunotherapeutic Effect of Rasayanas in Cancer: A Conceptual Study

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