(R)-1-(4-Bromobenzoyl)-4-(1-phenylpropyl)thiosemicarbazide

Abstract

The title compound, C17H18BrN3OS, is an important inter­mediate for the synthesis of biologically active heterocyclic compounds. The thio­urea group is approximately planar. The crystal structure is stabilized by inter­molecular N—H⋯O hydrogen-bonding inter­actions.

1-(4-Ethoxybenzoyl)-4-(4-methoxyphenyl)thiosemicarbazide

“…Thiosemicarbazides represent a class of versatile precursors for the syntheses of various nitrogen heterocycles (Kucukguzel et al, 2007;Al-Masoudi et al, 2006;Tozkoparan et al, 2007;Tomascikava et al, 2008;Serwer et al 2008;Serwar et al 2009). The thiosemicarbazide moiety possesses substantial pharmaceutical potential such as anti-tumor (Angelusiu et al, 2009), tyrosinase inhibitor (Liu et al, 2009) and antioxidant (Ghosh et al, 2009) properties.…”