Puerariae Radix protects against ulcerative colitis in mice by inhibiting NLRP3 inflammasome activation
Yu Ga,
Yuanyuan Wei,
Qingyu Zhao
et al.
Abstract:Ulcerative colitis (UC) is a common infl ammatory disease of the gastrointestinal tract. Traditional Chinese medicine (TCM) has long been used in Asia as a treatment for UC and Puerariae Radix (PR) is a reliable anti-diarrheal therapy. The aims of this study were to investigate the protective effect of PR using the dextran sulfate sodium salt (DSS)-induced UC model in mice and identify molecular mechanisms of PR action. The chemical constituents of PR via ultra-performance liquid chromatography/tandem mass spe… Show more
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