Pseudomonas aeruginosainfection increases palmitoyl carnitine release by host-derived extracellular vesicles
Rajalakshmy Ayilam Ramachandran,
Hamid Baniasadi,
Danielle M. Robertson
Abstract:Pseudomonas aeruginosa(PA), an opportunistic gram-negative pathogen, is the most common pathogen identified in all culture positive cases of infectious keratitis. Extracellular vesicles (EVs) are released by most cells in the body and function in intercellular communication. We have previously reported a change in the proteome of host-derived EVs from corneal epithelial cells during PA infection. In the present study, we investigated changes in the metabolome of host-derived EVs from PA infected (PA-C EVs) and… Show more
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