Panax ginseng:Relation between Age of Plant and Content of Ginsenosides

Abstract

The roots of PANAX GINSENG C. A. Meyer contain a relatively high percentage of ginsenosides from their first year of life onwards. Since the major development of weight of roots occurs between the 4th and 5th year of life, it has been established that the highest yield of ginsenosides and therefore the best time for harvesting the roots is at the end of the summer of the 5th year.

Identification of antidepressant-like ingredients in ginseng root (Panax ginseng C.A. Meyer) using a menopausal depressive-like state in female mice: participation of 5-HT2A receptors

“…Red and white ginseng powders (less than 200 mesh), supplied by the Korea Ginseng Corporation (formerly, Korean Ginseng and Tobacco Monopoly Corporation in the Republic of Korea), were administered orally at three dose levels (100, 200, and 400 mg/kg/day) in a distilled water suspension. Because the content of sapogenins depends upon the age of the ginseng root (Soldati and Tanaka 1984), we used materials extracted from 6-year-old P. ginseng. Ginseng saponin (25, 50, and 100 mg/kg/day) or non-saponin fractions (50, 100, and 200 mg/kg/day) and pure ginsenosides (Rb 1 , Rg 1 , and Ro) were administered intraperitoneally at three dose levels (2.5, 5, and 10 mg/kg/ day) in an isotonic saline solution because ginsenosides are enzymatically metabolized in the digestive tract of rodents (e.g., Odani et al 1983;Hasegawa et al 1996), particularly by removing glucose.…”

Chemical and biological evaluation of proteins and mucilages from roots and seeds ofGlossostemon bruguieri Desf. (Moghat)

“…Previous work revealed that the fat and mucilage contents varied with age of the roots [3]. Also it was reported that the ginsenoside content and, therefore the therapeutic value of ginseng roots may vary due to their age [4]. Accordingly, the root age should be considered, since the moghat roots available in the markets might be one, two or three years old.…”

Effects of Root Extracts from <i>Panax ginseng</i> C. A. Meyer (Araliaceae) of Different Ages on K562 Cells

“…Some evidence from previous studies also clearly indicated that Rh 2 and compound K have strong effects on some cultured cancer cells in vitro experiments [13][14][15][16][17][18]. Moreover, it has been reported that ginsenosides in ginseng roots will increase slowly in the first several years and then increase sharply in the fifth and sixth years [19].…”