<i>Neuronal Ensembles: Strategies for Recording and Decoding</i>. Howard B. Eichenbaum , Joel L. Davis

Krichmar, Jeff

doi:10.1086/393137

Cited by 1 publication

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“…The focus of Basic Protocol 2 is the optimization of experimental parameters to reduce confounds and improve experimental validity. This section does not cover procedures specific to post-processing of data or relevant statistical analyses, but several previously published protocols can be found on these topics, especially those related to general recommendations for analyses and assessing recording quality (Eichenbaum & Davis, 1998;Friend et al, 2015;Harris et al, 2017;Mohapatra et al, 2022;Rieke et al, 1999;Zhao et al, 2014;Journal of Neuroscience, 2018).…”

Section: Optimizing Experimental Design and Parametersmentioning

confidence: 99%

Investigating Neural Correlates of Behavior Through In Vivo Electrophysiology

Halladay

2023

Current Protocols

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Behavioral neuroscience has long relied on in vivo electrophysiology to provide spatially and temporally precise answers to complex questions about the neural dynamics underlying sensory processing and action execution. Investigating the neural correlates of behavior can be challenging in freely behaving animals, especially when making inferences related to internal states that are temporally or conceptually ambiguous, such as decision‐making or motivation. This necessitates careful creation of appropriate and rigorous controls and awareness of the many potential confounds when attributing neural signals to animal behavior. This article discusses fundamental considerations for the optimal design and interpretation of in vivo rodent electrophysiological recording experiments and focuses on the different optimization strategies required when investigating neural encoding of external stimuli versus free behavior. The first protocol offers suggestions specific to intracranial surgical implantation of multielectrode arrays. The second protocol delves into optimization strategies and tips useful for designing and interpreting recording experiments conducted in freely behaving rodents. © 2023 Wiley Periodicals LLC. Basic Protocol 1: Surgical implantation of the multielectrode array Basic Protocol 2: Optimizing experimental design and parameters

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Section: Optimizing Experimental Design and Parametersmentioning

confidence: 99%

Investigating Neural Correlates of Behavior Through In Vivo Electrophysiology

Halladay

2023

Current Protocols

View full text Add to dashboard Cite

show abstract

Neuronal Ensembles: Strategies for Recording and Decoding. Howard B. Eichenbaum , Joel L. Davis

Cited by 1 publication

References 0 publications

Investigating Neural Correlates of Behavior Through In Vivo Electrophysiology

Investigating Neural Correlates of Behavior Through In Vivo Electrophysiology

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