<i>Nectandra megapotamica</i>(Spreng.) Mez.: phytochemical characterization and neutralizing effect on<i>Bothrops diporus</i>venom

Torres, Ana; Camargo, Francisco J.; Ricciardi, Gabriela; Ricciardi, Armando; Dellacassa, Eduardo

doi:10.1080/10412905.2014.882277

Cited by 12 publications

(4 citation statements)

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“…Previous studies on this species have reported the presence of neolignans, phenylpropanoids, lignans, and tetrahydrofurans with cytotoxic activity against leukemic cells [13], antileishmanial and antimalarial [14], trypanocidal [11], and analgesic and anti-inflammatory activities [15], confirming the properties indicated by traditional medicine. The essential oils of this plant have been reported to possess several beneficial properties such as anti-inflammatory and antitumoral activities [16] and could also neutralize the effect induced by the venom of Bothrops diporus [17].…”

Section: Introductionmentioning

confidence: 99%

Influence of Monoterpenes in Biological Activities of Nectandra megapotamica (Spreng.) Mez Essential Oils

et al. 2019

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Investigating the influence of seasonal variations on biological activities is important for pharmacological studies and metabolic engineering. Therefore, this study was conducted to determine the variation of the chemical composition of essential oils obtained from Nectandra megapotamica leaves, collected at different stages of plant development, as well as its influence on the biological activities. A total of 38 compounds were identified that accounted for 97–99.2% of the chemical composition of the oils. Major differences were observed in the monoterpenic fraction, representing 5.1% of the compounds identified in the productive rest phase to 37.1% in the blooming phase. Bicyclogermacrene and germacrene D were the predominant compounds identified in the oil of all collections. Furthermore, limonene, β-pinene, and spathulenol were identified predominantly in the samples of blooming and fruiting phases. The oils exhibited significant antichemotactic activity and different effects in scavenging the radical 2,2-diphenyl-1-picrylhydrazyl. Variations were also observed in the antifungal activity, with the minimum inhibitory concentrations ranging from 125 to 500 μg/mL. These results demonstrate the influence of monoterpenes, primarily limonene, α-pinene, and β-pinene, on the bioactivities of the oil. Studies investigating the variations in the chemical composition of essential oil may offer a strategy to produce a compound or a group of compounds of interest to industries with a specific pharmacological focus.

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Section: Introductionmentioning

confidence: 99%

Influence of Monoterpenes in Biological Activities of Nectandra megapotamica (Spreng.) Mez Essential Oils

et al. 2019

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“…The various biological activities described to essential oil (EO) of N. megapotamica and/ or its components have aroused interest of Latin American researchers working in the area of its occurrence. Among them are noteworthy the antiinflammatory activity described by Apel et al (2006) for EO obtained from specimens in Cananéia, SP, the anesthetic action on fat snook (Centropomus parallelus) obtained with EO of specimens occurring in Santa Maria, RS (Tondolo et al 2013), the inhibition of hemolytic activity of jararaca (Bothrops diporus) venom with EO obtained from plant material collected in Corrientes, Argentina (Torres et al 2014), and the insecticidal activity against larvae of Coenagrionidae (Silva et al 2014). All the described effects are directly influenced by the chemical composition of EO, and knowledge about the income of this extractive is fundamental to the planning and execution of further studies aiming practical applications.…”

Section: Introductionmentioning

confidence: 99%

Seasonal influence on the essential oil production of Nectandra megapotamica (Spreng.) Mez

Amaral

Tondolo

Schindler

et al. 2015

Braz. arch. biol. technol.

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“…The essential oil of Nectandra megapotamica has already revealed to have microbial activity against Staphylococcus aureus, anti-inflammatory and antitumoral activity, indicating its pharmacological potential [5]. Some organ-based preparations of this species have been shown to inhibit hemolytic, coagulant and proteolytic activities of venom of Bothrops diporus [6]. The essential oil showed also an anesthetic effect on Centropomus parallelus [7], as well as antifungal and antimicrobial activities.…”

Section: Introductionmentioning

confidence: 99%

Use of Frozen Leaves for Morpho-anatomical Characterization of Nectandra megapotamica (Spreng.) Mez., Lauraceae

Costa

Reiniger

Trindade

et al. 2019

Braz. arch. biol. technol.

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Nectandra megapotamica (Spreng.) Mez. it is a native tree species of the Atlantic Forest, commonly known as canela-preta. The species has some antiinflammatory, antitumor and antirheumatic properties among others. In this work the use of frozen plant material for microscopy analysis was tested. In addition, the leaf morpho-anatomy of the species was characterized which allowed to perform a structural description and to identify structures of secretion and storage of essential oil. The plant material was prepared for analyzes in optical, fluorescence and scanning electron microscopy. The leaf anatomy shows glabrous epidermis, unistratified, paracytic stomata, absence of trichomes, polyhedral epidermal cells. Some typical family characteristics were observed as a closed arc-shaped bicollateral bundle HIGHLIGHTS• It was possible to obtain a morpho-anatomical characterization from frozen leaf samples.• Typical structures of the family Lauraceae described by other authors were identified.• Secretion and storage of essential oil occurs in secretory cavities.2 Costa, L.S.; et al.

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Nectandra megapotamica(Spreng.) Mez.: phytochemical characterization and neutralizing effect onBothrops diporusvenom

Cited by 12 publications

References 10 publications

Influence of Monoterpenes in Biological Activities of Nectandra megapotamica (Spreng.) Mez Essential Oils

Influence of Monoterpenes in Biological Activities of Nectandra megapotamica (Spreng.) Mez Essential Oils

Seasonal influence on the essential oil production of Nectandra megapotamica (Spreng.) Mez

Use of Frozen Leaves for Morpho-anatomical Characterization of Nectandra megapotamica (Spreng.) Mez., Lauraceae

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