N-Methyl-N-cis-styrylcinnamamide monohydrate, a compound of Clausenaminade from Clausena lansium (Lour.) Skeels

Abstract

Key indicatorsSingle-crystal X-ray study T = 293 K Mean (C-C) = 0.003 Å R factor = 0.042 wR factor = 0.123 Data-to-parameter ratio = 17.1 For details of how these key indicators were automatically derived from the article, see ExperimentalPulverized dried seeds were extracted with 80% ethanol solution three times under reflux. The extract was concentrated in vacuo, then

N-Methyl-N-styrylcinnamamide (lansamide) fromClausena lansiumin Vietnam

“…The title compound, C 18 H 17 NO, was isolated from the seeds of Clausena lansium (wampee) (Rutaceae). The X-ray crystal structure analysis confirmed its chemical identity and revealed that it is solvent-free, in contrast to the previously reported monohydrate [Huang, Ou & Tang (2006). Acta Cryst.…”

“…For the structure of the monohydrate, see: Huang et al (2006). For medicinal applications, see: Loi (2001).…”

“…The X-ray structure of the monohydrate of (I) was reported recently (Huang et al, 2006) wherein it was reported that "the corresponding anhydrous compound is a pale-yellow liquid at room temperature". Surprisingly, we could grow paleyellow crystals of the water-free form from n-hexane and its X-ray structure, which is subject of this study, was carried out to confirm its chemical identity.…”