<i>N</i>-Methoxy-<i>N</i>-methylacetamide

Harris, Thomas M.

doi:10.1002/047084289x.rm103

Cited by 1 publication

(1 citation statement)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The stereochemistry of nucleophilic addition to activated alkynes for the preparation of important functional groups such as enamines and cyclic compounds has been well studied 1–6. The preparation of enamines by the reaction of para‐ and meta‐substituted anilines and methyl propiolate was particularly investigated by Heindel et al 7,8.…”

Section: Introductionmentioning

confidence: 99%

Kinetics and mechanism study of aniline addition to ethyl propiolate

Nori‐Shargh

Soltani

Saroogh-Farahani

et al. 2005

Int J of Chemical Kinetics

View full text Add to dashboard Cite

The kinetics of the addition reaction of aniline to ethyl propiolate in dimethylsulfoxide (DMSO) as solvent was studied. Initial rate method was used to determine the order of the reaction with respect to the reactants, and pseudo-first-order method was used to calculate the rate constant. This reaction was monitored by UV-Vis spectrophotometer at 399 nm by the variable time method. On the basis of the experimental results, the Arrhenius equation for this reaction was obtained as log k = 6.07 − (12.96/2.303RT). The activation parameters, E a , H # , G # , and S # at 300 K were 12.96, 13.55, 23.31 kcal mol −1 and −32.76 cal mol −1 K −1 , respectively. The results revealed a first-order reaction with respect to both aniline and ethyl propiolate. In addition, based on the experimental results and using also density functional theory (DFT) at B3LYP/6-31G* level, a mechanism for this reaction was proposed. C 2005 Wiley Periodicals, Inc. Int J Chem Kinet 38: [144][145][146][147][148][149][150][151] 2006

show abstract

Section: Introductionmentioning

confidence: 99%