N-[2-(4-Bromophenyl)-5-methyl-4-oxo-1,3-thiazolidin-3-yl]pyridine-3-carboxamide

Abstract

In the title compound, C16H14BrN3O2S, the atoms of the 1,3-thia­zolidine group, except for the N and the C atoms attached to the bromo­benzene ring, are disordered over two sets of sites with occupancies of 0.605 (13) and 0.395 (13). The benzene and pyridine rings make a dihedral angle of 86.2 (2)°. In the crystal, mol­ecules are linked by inter­molecular N—H⋯N and C—H⋯O hydrogen bonds, forming a three-dimensional network. Furthermore, there is a π–π stacking inter­action [centroid–centroid distance = 3.758 (2) Å] between the pyridine and benzene rings.

Stereochemical Investigations of DiastereomericN-[2-(Aryl)-5-methyl-4-oxo-1,3-thiazolidine-3-yl]-pyridine-3-carboxamides by Nuclear Magnetic Resonance Spectroscopy (1D and 2D)

“…The solid thus obtained was washed with water, dried, and recrystallized from ethanol. Some spectral and X-ray crystallographic data of compounds 2a, 2b, and 2f were reported regardless of stereochemistry in our previously published articles [34][35][36]. [36] (for 1 H NMR data of other protons see Table 1).…”

“…Some spectral and X-ray crystallographic data of compounds 2a, 2b, and 2f were reported regardless of stereochemistry in our previously published articles [34][35][36]. [36] (for 1 H NMR data of other protons see Table 1). 13 [34] (for 1 H NMR data of other protons see Table 1).…”