“…Pyrazole derivatives are heterocyclic compounds recognized to possess a wide range of biological and pharmacological activities. 1 , 2 The unique properties of pyrazoles have been attributed to the electrophilic substitution reactions that occur specially at position 4, and nucleophilic attacks that occur at positions 3 and 5, thus leading to diverse pyrazole structures with broad potential applications in areas such as medicine, agriculture and technology. 3 , 4 , 5 In addition, compounds containing a pyrazole nucleus have been reported to be anti-inflammatory, antiviral, anticancer, antiparasitic, antibacterial, antirheumatoid, antidepressant, analgesic, antinociceptive, antihypertensive, antipyretic and antifungal agents.…”