Mycoplasma hominis periaortic abscess following heart–lung transplantation

Abstract

We report the first case of Mycoplasma hominis periaortic abscess after heart-lung transplantation. The absence of sternal wound infection delayed the diagnosis, but the patient successfully recovered with debridement surgeries and long-term antibiotic therapy. Owing to the difficulty in detection and the intrinsic resistance to beta-lactams, M. hominis infections are prone to being misdiagnosed and undertreated. M. hominis should be suspected in cases where conventional microbiological identification and treatment approaches fail.

Mycoplasma hominis bursitis in a simultaneous pancreas‐kidney transplant recipient: case report and literature review

“…Perinephric fluid collection was the most common site occurring in 38% of cases (10 out of 26 cases), followed by wound and urinary tract infection in 27% of cases (7 out of 26 cases) each. Other sites include peritoneal fluid, blood, abdominal collections, and joints 2‐43 . This is the first reported case of infective bursitis caused by M. hominis in the post‐transplant setting.…”

“…Extragenital infections caused by M. hominis are being increasingly recognized in renal and SPK transplant recipients with 26 reported cases of M hominis infections in the English medical literature (Table 1). 2‐43 However, the true incidence and outcomes related to this infection in renal transplant recipients remain unknown. Among the reported cases, the number of infections was similar between females (14 cases) and males (11 cases) with one case report not specifying the patient's sex.…”

Mycoplasma and Ureaplasma Infections in Transplantation: A Big Impact Despite the Lack of a Cell Wall

“…Another manifestation was a periaortic abscess formation caused by M. hominis without presence of a sternal wound infection following combined heart-lung transplantation. The authors highlighted the need for considering M. hominis as pathogen, once conventional microbiological identification and empiric treatment failed [18]. In this case, a combined approach of surgical revision and prolonged antimicrobial therapy (3 months) was successful.…”

Bacterial infections in lung transplantation

“…have been associated with infections of the anastomosis and stents (28). Mycoplasma hominis can cause intra-thoracic infections (29,30). Clostridium difficile infection (CDI) is also a frequent complication (31,32).…”

“…Mycoplasma hominis may cause infection in LTRs (29,30). Another infection, which may be donor-derived, with unusual consequences is infection with Ureaplasma urealyticum or Ureaplasma parvum (153)(154)(155)(156).…”