Mucuna pruriens treatment shows anti-obesity and intestinal health effects in obese rats

Abstract

This study evaluated anti-obesity effect and intestinal health of obese rats treated with MP, focusing on food consumption and somatic, biochemical, and histological parameters. 32 Wistar rats with ± 40...

Mucuna pruriens Constituted Diet Ameliorates Manganese-Induced Behavioural Deficit and Histological Alterations in the Brains of Rats

“…This result therefore suggests that Mn and M. pruriens leaves could play a role in decreasing body However, the data also suggest that M. pruriens impact on body weight reduction could be dose dependent as 20% constituted M. pruriens feed showed a more drastic decrease in body weight compared to control rats. This finding is supported by previous studies (Salaam et al 2019;Tavares et al 2021), who reported decreased body weight and physical activities of rats treated with ethanol extract of M. pruriens leaves, and attributed same to the metabolic changes produced by the chemical constituents.…”

Effects of supplementation of tropical fruit processing by-products on lipid profile, retinol levels and intestinal function in Wistar rats

“…Animal faeces were collected on the 26 th to 28 th days of the experiment to obtain samples in representative quantities for analysis (Batista et al 2018, Tavares et al 2021. Part of the faecal samples was collected fresh for bacterial count analysis and part was stored in a freezer -20°C for pH and moisture analysis.…”

Extra virgin coconut oil (Cocos nucifera L.) intake shows neurobehavioural and intestinal health effects in obesity-induced rats

“…The cafeteria diet consisted of commercial feed (Presence®, Paulínia, Brazil) and processed foods such as cookies, corn chips, sausages, cakes, and chips, among other foods considered hypercaloric. 11,29,33 The processed foods were distributed on a menu, in which four foods were offered and commercial feed on each day of the week (Table S2 †). The respective foods were administered separately, served in 5 cm pieces inside glass jars with quantity ad libitum.…”

“…The healthy groups received a commercial feed or control diet (Presence®, Paulínia, Brazil) with 3.1 kcal g −1 , 57 kcal % carbohydrates, 28 kcal % protein, 14 kcal % lipids (Table S3 †). 29,33 Food consumption and food preference (in grams) for the OG and OGCO groups were evaluated daily and calculated from the amount offered of processed foods and commercial feed minus leftovers (waste), respectively. Each day, the obesity-induced rats had the option of consuming the commercial chow (Presence®, Paulínia, Brazil) and/or four different foods, which made it possible to analyse the food preference of the OG and OGCO rats over the 16 weeks of the study.…”

“…In turn, the food consumption (in grams) of the HG and HGCO rats was also evaluated daily and took into account the amount of commercial feed or control diet (Presence®, Paulínia, Brazil) offered minus leftovers (waste) from this commercial feed during the 16 weeks of the study, with energy intake being calculated from the consumption in grams of feed and the nutritional information contained in the feed label. 11,29,33 The HGCO and OGCO groups received E-VCO (3000 mg per kg of body weight) daily by gavage during the final eight weeks of the experiment, while the control groups (HG and OG) received filtered water. The E-VCO dose was chosen based on the average amount consumed by the human population 34 which was then converted for rats, 34 as it has also demonstrated beneficial effects on adiposity in the obese rodent.…”