<i>Moringa oleifera</i>: a food plant with multiple medicinal uses

Anwar, Farooq; Latif, Sajid; Ashraf, Muhammad; Gilani, Anwarul Hassan

doi:10.1002/ptr.2023

Cited by 1,498 publications

(1,225 citation statements)

References 74 publications

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“…Moringa oleifera revealed the presence of glucosinolates, isothiocyanates, carotenoids, vitamins, high proteins and carbohydrates (Fahey;Paliwal et al;Anwar et al;Junqueira & Carneiro, 2007). Hence, the plant is of high medicinal and nutritive values to both humans and livestocks (Junqueira & Carneiro).…”

Section: Phytochemical Screenings Of Different Parts Ofmentioning

confidence: 99%

“…It is popularly called 'the miracle tree' with potentials for the treatment of various diseases such as cancer, hypertension and diabetes mellitus (Fahey; Paliwal et al). Moringa oleifera's leaves have been traditionally used as antidiabetic, anti-bacterial, anti-headache, anti-hypertensive, antifever and anti-inflammatory herbal drug (Fahey;Paliwal et al;Anwar et al, 2007). Various parts of the plant have been scientifically established to possess some medicinal properties such as abortifacient (root, flower and gum), anti-hypertensive (flower and seed), hypolipidemic (flower), anti-inflammatory (root and flower) and anti-ulcerogenic (stem bark) potentials (Fahey; Paliwal et al; Anwar et al).…”

Section: Introductionmentioning

confidence: 99%

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Moringa oleifera Impairs the Morphology and Functions of the Kidney in Adult Wistar Rats

Akinlolu¹,

Ghazali²,

Ameen³

et al. 2014

Int. J. Morphol.

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SUMMARY:We tested the hypothesis that Moringa oleifera impairs the morphology and functions of the kidney in rats. Twentyfour adult male Wistar rats were employed in the study. Rats of Control Group I received physiological saline while rats of Groups II -IV received 250, 500 and 750 mg/kg bodyweight of methanolic extract of Moringa oleifera respectively for twenty one days. No behavioral anomalies were observed in rats of Groups I -IV. Rats of Control Group I gained statistically significant increased bodyweight while rats of Groups II -IV experienced non-significant decreased bodyweight during experimental procedure. (P≤0.05). No statistical significant differences (P≤0.05) were observed in the analyses of the relative weights of kidneys of rats of Groups I -IV. Histological examinations showed normal cyto-architecture of the kidneys of rats of Group I while the Capsular spaces of the kidneys of rats of Groups II -IV appeared wider than those of Group I. Statistical analyses showed significant higher levels (P≤0.05) of Alanine and Aspartate Transaminases, and serum urea in rats of Groups II -IV in a non-dose-dependent manner when compared to rats of Group I. Our findings are consistent with the stated hypothesis.

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Section: Phytochemical Screenings Of Different Parts Ofmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Moringa oleifera Impairs the Morphology and Functions of the Kidney in Adult Wistar Rats

Akinlolu¹,

Ghazali²,

Ameen³

et al. 2014

Int. J. Morphol.

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“…In addition to its compelling water purifying powers and high nutritional value, M. oleifera is very important for its medicinal value. Various parts of this plant act as cardiac and circulatory stimulants, possess antitumour, antipyretic, antiepileptic, anti-inflammatory, antiulcer, antispasmodic, diuretic 4 , antihypertensive, cholesterol lowering 5 , and antioxidant, antidiabetic, hepatoprotective, antibacterial and antifungal activities 1,6 , aphrodisiac, antihelmintic, analgesic activities 7,8 , Rubefacient, Vesicant 9 . According to Unani literature it possesses many actions like Moohallil-e-Waram, Muqawwi-e-Bah, Mushtahi, Qatile Kiram-e-Amaa 10,11 , so medicinally used in Waja-ul-Mafasil, Waja-ul-Qutu, Zof-eIshteha 12,13 .…”

Section: Moringa Oleifera Lam (Family Moringaceae and Genus Moringa)mentioning

confidence: 99%

Determination of Heavy Metals, Aflatoxins, Microbial Loads and Pesticides Residue in Sehjana (Moringa Oleifera Lam) Fruits/Pods

Khan¹,

Khan²,

Naseem³

et al. 2017

Int. Res. J. Pharm.

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Safety study of herbal drugs and food item is now mandatory as per WHO guidelines, to prevent the toxicity due to the material found in the soil and the environment. It includes determination of aflatoxin, heavy metal, pesticidal residue, microbial load. Therefore, the present study was aimed to evaluate safety parameter in Sehjana (Moringa oleifera Lam) Fruits powder, a very common drug used in Unani and Ayurvedic system of medicine for its cardiac and circulatory stimulant, and anti-oxidant, anti-inflammatory effect used in acute rheumatism, Asthma, gout, paralysis. Study reveals the presence of microbial loads, and heavy metals, lead, cadmium, mercury, and arsenic within permissible limit as per WHO guidelines, while aflatoxins, pesticides was found to be absent in the crude drug sample, indicating that the drug is free from toxicity.

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“…It has an impressive range of medicinal uses with high nutritional value. In addition to its compelling water purifying powers and high nutritional value, Moringa oleifera is very important for its medicinal value (Anwar et al, 2007).…”

Section: * Corresponding Authormentioning

confidence: 99%

Molecular Docking Studies of Phytoconstituents Identified in Crocus sativus, Curcuma longa, Cassia occidentalis and Moringa oleifera on Thymidylate Synthase and ndash; An Enzyme Target for Anti-Cancer Activity

Heble¹,

Mavillapalli²,

Selvaraj³

et al. 2016

J App Pharm Sci

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The aim and objective of the present study is to perform in-silico docking analysis of the major active constituents identified in four Indian medicinal plants namely Crocus sativus, Curcuma longa, Cassia occidentalis and Moringa oleifera for anti-cancer activity. In-silico docking analysis was performed by using Molegro Virtual Docker (MVD). The parameter used for the docking analysis are MolDock score, Rerank score and H-Bond interactions (binding energy). The target for anti-cancer activity is thymidylate synthase. The XRay crystal co-ordinate of thymidylate synthase (PDB ID-1HVY) was retrieved from protein data bank in .pdb format. The phytoconstituents of four medicinal plants were retrieved from PubChem compound database in .mol format. The standard drugs Ralitrexed, 5-Fluorouracil and Vinblastine were obtained from the drug bank in .mol format for comparison. The comparative anti-cancer activity of the phytoconstituents of four medicinal plants are analysed by docking score and binding energy. It was analysed from the parameters of docking that the phytoconstituents from Crocus sativum showed better anti-cancer activity compared to that of the standard drugs.

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Moringa oleifera: a food plant with multiple medicinal uses

Abstract: Moringa oleifera

Cited by 1,498 publications

References 74 publications

Moringa oleifera Impairs the Morphology and Functions of the Kidney in Adult Wistar Rats

Moringa oleifera Impairs the Morphology and Functions of the Kidney in Adult Wistar Rats

Determination of Heavy Metals, Aflatoxins, Microbial Loads and Pesticides Residue in Sehjana (Moringa Oleifera Lam) Fruits/Pods

Molecular Docking Studies of Phytoconstituents Identified in Crocus sativus, Curcuma longa, Cassia occidentalis and Moringa oleifera on Thymidylate Synthase and ndash; An Enzyme Target for Anti-Cancer Activity

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