mleS in Staphylococcus aureus Contributes to Microaerobic Metabolic Activity, Abscess Formation, and Survival in Macrophages

Abstract

Given the importance of metabolic adaptation during infection, new insights are required regarding the pathogenesis of S. aureus , particularly for epidemic clones. We accordingly investigated the role of metabolic determinants that are unique to the epidemic clones ST59 and ST398.