1996
DOI: 10.1016/0014-5793(96)00543-1
|View full text |Cite
|
Sign up to set email alerts
|

MBA1 encodes a mitochondrial membrane‐associated protein required for biogenesis of the respiratory chain

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
2
1

Citation Types

2
32
0

Year Published

1996
1996
2016
2016

Publication Types

Select...
8
1

Relationship

1
8

Authors

Journals

citations
Cited by 23 publications
(34 citation statements)
references
References 24 publications
2
32
0
Order By: Relevance
“…2C). Mba1 has been implicated in the process of insertion of newly synthesized translation products by aligning the mitochondrial ribosome with the membrane insertion machinery (2225). To support the mass spectrometric data, Cox20 ProtA -containing complexes were purified from mitochondria, and the purified fraction was analyzed by Western blotting (Fig.…”
Section: Resultsmentioning
confidence: 99%
See 1 more Smart Citation
“…2C). Mba1 has been implicated in the process of insertion of newly synthesized translation products by aligning the mitochondrial ribosome with the membrane insertion machinery (2225). To support the mass spectrometric data, Cox20 ProtA -containing complexes were purified from mitochondria, and the purified fraction was analyzed by Western blotting (Fig.…”
Section: Resultsmentioning
confidence: 99%
“…Cotranslational insertion of the Cox2 N-terminal tail together with the first transmembrane span depends on the export machinery, Oxa1 (1719). The peripheral inner membrane protein Mba1 cooperates with Oxa1 in the insertion of mitochondrial translation products (2025). Mba1 is thought to align the ribosomal exit tunnel with the export machinery (23).…”
Section: Introductionmentioning
confidence: 99%
“…This module was characterized by enrichment for two functional categories: "respiration" (10 genes) and "mitochondrial biogenesis" (14 genes). The category of "respiration" comprised genes encoding various subunits of the F o (ATP4, ATP14, ATP18, and ATP20) and F 1 (ATP3 and ATP15) domains of mitochondrial ATP synthase (16) but also COX23, COX14, MAM33, and MBA1, involved in the assembly of respiratory complexes in mitochondria (3,27,60,67). The relationship between Zn availability and these proteins remains unclear, although cytochrome c oxidase activity has been shown to be inhibited by Zn.…”
Section: Resultsmentioning
confidence: 99%
“…Export of the Cox2p N-terminal hydrophilic domain depends on Oxa1p, a translocase component embedded in the inner membrane (Bonnefoy et al, 1994a;Altamura et al, 1996;He and Fox, 1997;Hell et al, 1997;Kermorgant et al, 1997;Hell et al, 1998). Another inner membrane protein, Mba1p (Rep and Grivell, 1996), is also involved in N-tail export (Preuss et al, 2001). After export, a 15-amino acid leader peptide is removed from the N terminus by a protease comprised of Imp1p, Imp2p, and Som1p (Schneider et al, 1991;Nunnari et al, 1993;Jan et al, 2000), in a reaction facilitated by the interaction of preCox2p with the inner membrane protein Cox20p (Hell et al, 2000).…”
Section: Introductionmentioning
confidence: 99%