<i>Macracanthorhynchus ingens</i>Infection in an 18-Month-Old Child in Florida: A Case Report and Review of Acanthocephaliasis in Humans

Mathison, Blaine A.; Bishop, Henry; Sanborn, Chad R.; Souza, Samaly dos Santos; Bradbury, Richard S.

doi:10.1093/cid/ciw543

Cited by 19 publications

(10 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Acanthocephala (thorny-headed worms) are endoparasites of jaw-bearing vertebrates (Gnathostomata) including humans [1][2][3][4]. In their digestive tract, the worms usually grow to adults of several millimeters to a few centimeters in length, followed by heterosexual reproduction.…”

Section: Introductionmentioning

confidence: 99%

The genome, transcriptome, and proteome of the fish parasite Pomphorhynchus laevis (Acanthocephala)

et al. 2020

View full text Add to dashboard Cite

Thorny-headed worms (Acanthocephala) are endoparasites exploiting Mandibulata (Arthropoda) and Gnathostomata (Vertebrata). Despite their worldwide occurrence and economic relevance as a pest, genome and transcriptome assemblies have not been published before. However, such data might hold clues for a sustainable control of acanthocephalans in animal production. For this reason, we present the first draft of an acanthocephalan nuclear genome, besides the mitochondrial one, using the fish parasite Pomphorhynchus laevis (Palaeacanthocephala) as a model. Additionally, we have assembled and annotated the transcriptome of this species and the proteins encoded. A hybrid assembly of long and short reads resulted in a near-complete P. laevis draft genome of ca. 260 Mb, comprising a large repetitive portion of ca. 63%. Numbers of transcripts and translated proteins (35,683) were within the range of other members of the Rotifera-Acanthocephala clade. Our data additionally demonstrate a significant reorganization of the acanthocephalan gene repertoire. Thus, more than 20% of the usually conserved metazoan genes were lacking in P. laevis. Ontology analysis of the retained genes revealed many connections to the incorporation of carotinoids. These are probably taken up via the surface together with lipids, thus accounting for the orange coloration of P. laevis. Furthermore, we found transcripts and protein sequences to be more derived in P. laevis than in rotifers from Monogononta and Bdelloidea. This was especially the case in genes involved in energy metabolism, which might reflect the acanthocephalan ability to use the scarce oxygen in the host intestine for respiration and simultaneously carry out fermentation. Increased plasticity of the gene repertoire through the integration of foreign DNA into the nuclear genome seems to be another underpinning factor of the evolutionary success of acanthocephalans. In any case, energy-related genes and their proteins may be considered as candidate targets for the acanthocephalan control.

show abstract

Section: Introductionmentioning

confidence: 99%

The genome, transcriptome, and proteome of the fish parasite Pomphorhynchus laevis (Acanthocephala)

et al. 2020

View full text Add to dashboard Cite

show abstract

“…Moniliformis moniliformis prevalence within the population of wild rats was low but similar to studies reported from Spain (Galán- Puchades et al., 2018), Malaysia (Mohd Zain et al., 2012) and Jamaica (Waugh et al., 2006). Human infection results from the ingestion of infected insects and sporadic cases of human infections have been reported from Florida (Mathison et al., 2016), Nigeria (Ikeh et al., 1992), Saudi Arabia (Sahar et al., 2010) and Iran (Maraghi et al., 2014). To date, human infections with M. moniliformis have not been reported in the Caribbean region.…”

Section: Discussionmentioning

confidence: 99%

Internal parasitic burdens in brown rats (Rattus norvegicus) from Grenada, West Indies

Coomansingh-Springer

Vishakha

Acuña

et al. 2019

Heliyon

View full text Add to dashboard Cite

This study identified the endoparasites in Brown rat ( Rattus norvegicus) during May to July 2017 in Grenada, West Indies. A total of 162 rats, 76 females and 86 males were trapped from St. George and St. David parishes in Grenada. The collected fecal samples were examined for parasitic eggs and/or oocysts using simple fecal flotation technique. Adult parasites found in the intestinal tract were examined for identification. The overall prevalence of intestinal parasites among rats was 79 %. Ten helminth species were recovered, several of which were reported for the first time in rodents in Grenada. The internal parasites consist of seven nematodes ( Angiostrongylus spp., Nippostrongylus braziliensis , Heterakis spumosa , Strongyloides ratti , Aspiculuris tetraptera , Syphacia spp. and Protospirura spp.), one cestode ( Hymenolepsis diminuta ), one acanthocephalan ( Moniliformis moniliformis ) and one protozoa species ( Eimeria spp.). The most prevalent zoonotic species were Angiostrongylus spp. (35.2%), Hymenolepsis diminuta (7.4%) and Moniliformis moniliformis (3.1%). Several nonzoonotic endoparasites; which included Nippostrongylus braziliensis (50.6%), Heterakis spumosa (15.4%), Strongyloides ratti (43.2%), Aspiculuris tetraptera (2.5%), Syphacia spp . (1.9%), Protospirura spp. (1.2%) and Eimeria spp. (4.7%) were also identified. The most prevalent parasites were Nippostrongylus brasiliensis (50.6%), Strongyloides ratti (43.2%) and Angiostrongylus spp. (35.2%). Co-infections occurred with up to six species per rat showing different combinations of parasitic infections.

show abstract

“…Taenia haeruca Pallas, 1776 Echinorhynchus gigas Bloch, 1782 Geographic distribution. Worldwide (Mathison et al 2016).…”

Section: Macracanthorhynchus Hirudinaceus (Pallas 1781)mentioning

confidence: 99%

“…Definitive hosts are pigs; dogs and other mammals can serve as reservoir hosts. Zoonotic in humans ( Mathison et al 2016 ).…”

Section: Checklist Of Eukaryotic Human Parasitesmentioning

confidence: 99%

“…Adults are large, pseudocoelomate animals that attach to the intestinal mucosa of the definitive host be means of a heavily armed proboscis. Human infection usually occurs from the ingestion of an infected intermediate or paratenic host ( Mathison et al 2016 ). The leeches ( Annelida : Hirudinea ) include blood-feeding members that will opportunistically feed on humans.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

An annotated checklist of the eukaryotic parasites of humans, exclusive of fungi and algae

Mathison¹,

Sapp²

2021

Self Cite

View full text Add to dashboard Cite

The classification of “parasites” in the medical field is a challenging notion, a group which historically has included all eukaryotes exclusive of fungi that invade and derive resources from the human host. Since antiquity, humans have been identifying and documenting parasitic infections, and this collective catalog of parasitic agents has expanded considerably with technology. As our understanding of species boundaries and the use of molecular tools has evolved, so has our concept of the taxonomy of human parasites. Consequently, new species have been recognized while others have been relegated to synonyms. On the other hand, the decline of expertise in classical parasitology and limited curricula have led to a loss of awareness of many rarely encountered species. Here, we provide a comprehensive checklist of all reported eukaryotic organisms (excluding fungi and allied taxa) parasitizing humans resulting in 274 genus-group taxa and 848 species-group taxa. For each species, or genus where indicated, a concise summary of geographic distribution, natural hosts, route of transmission and site within human host, and vectored pathogens are presented. Ubiquitous, human-adapted species as well as very rare, incidental zoonotic organisms are discussed in this annotated checklist. We also provide a list of 79 excluded genera and species that have been previously reported as human parasites but are not believed to be true human parasites or represent misidentifications or taxonomic changes.

show abstract

Macracanthorhynchus ingensInfection in an 18-Month-Old Child in Florida: A Case Report and Review of Acanthocephaliasis in Humans

Cited by 19 publications

References 5 publications

The genome, transcriptome, and proteome of the fish parasite Pomphorhynchus laevis (Acanthocephala)

The genome, transcriptome, and proteome of the fish parasite Pomphorhynchus laevis (Acanthocephala)

Internal parasitic burdens in brown rats (Rattus norvegicus) from Grenada, West Indies

An annotated checklist of the eukaryotic parasites of humans, exclusive of fungi and algae

Contact Info

Product

Resources

About