Listeria monocytogenesmeningitis in two immunocompetent children

Abstract

Listeria monocytogenes is an uncommon cause of bacterial meningitis beyond the neonatal period. Patients with immunosuppression or neoplastic disease are at increased risk of developing serious invasive disease, particularly meningitis. L. monocytogenes meningitis in two previously healthy, immunocompetent children aged 7 years and 18 months is described. One of them was successfully treated with ampicillin and amikacin. In the other there was resistance to ampicillin, and meropenem, vancomycin and amikacin were given. One patient developed unilateral abducens paralysis and inappropriate antidiuretic hormone secretion. L. monocytogenes should be suspected in children with bacterial meningitis who fail to respond to empirical antibiotic therapy.

Listeria monocytogenes in Fresh Produce: Outbreaks, Prevalence and Contamination Levels

“…The severity of listeriosis can range from mild gastroenteritis to severe disease conditions (septicemia, encephalitis, meningitis, abortions and stillbirths) and can result in a high fatality rate in immune-compromised populations [3]. Some people have a higher risk for developing listeriosis, such as the elderly (>65 years) [4,5,6], infants and toddlers (<5 years) [4,7,8,9], pregnant women [3,8], and the unborn [8,10]. About 17% of listeriosis cases occur in pregnant women [10].…”

A Case Report ofListeria monocytogenesMeningitis in a Child With Hyper-IgM Syndrome in a Resource-Limited Setting

“…Globally, most reported cases of L monocytogenes meningitis beyond infancy are seen in immunocompromised patients with comorbidities of childhood malignancy, diabetes mellitus, HIV infections, steroid therapy, and tuberculosis. 9,10 Congenital cellular, humoral, or combined immunodeficiency syndromes have also been reported with L monocytogenes meningitis. 3,9,10…”

Meningoencephalitis in immunocompetent young woman caused by Listeria monocytogenes: case report

“…Prikazana pacijentica nije pripadala niti jednoj od prethodno navedenih rizičnih skupina za razvoj bolesti. Podaci iz literature navode svega par slučajeva listerioze kod prethodno zdravih osoba, bez postojećih predispozicija i to uglavnom kod djece mlađe dobi [16][17][18][19][20] . Podatak o produženoj konzumaciji kolača sa svježim sirom (četiri dana uzastopno) potvrdio je karakteristično svojstvo listerije da izazove bolest nakon kontinuiranog unošenja u malim, infektivnim dozama zbog nastanka kumulativnog učinka.…”