Limosilactobacillus fermentumATG-V5 stimulates the immune response by enhancing gut microbiome and metabolite in a cyclophosphamide-induced immunosuppression mouse model
Arum Park,
Yeon-Hwa Park,
Yewon Kang
et al.
Abstract:Limosilactobacillus fermentum is known to exert immunomodulatory effects. In this study, we elucidated the immunoenhancing effects and mechanisms of a novel strain of Limosilactobacillus fermentum ATG-V5. Our findings demonstrate that ATG-V5 regulates the activation and proliferation of natural killer (NK) and T cells. It induced activation effects such as increased nitric oxide (NO) production, phagocytic capacity, and cytokine generation in Raw264.7 cells, which were confirmed to occur through the ERK and pp… Show more
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