Klebsiella pneumoniae Renal Abscess and Peritonitis in a Peritoneal Dialysis Patient: A Novel Route of Infection

Abstract

We present a peritoneal dialysis (PD) patient who had a renal biopsy performed during an episode of urosepsis and subsequently presented with a renal abscess at the biopsy site along with concurrent peritonitis. Microbiology from the PD effluent and from the renal abscess were both positive for We propose that the PD peritonitis was the result of seeding of the peritoneal cavity with bacteria from the renal abscess. Successful treatment was achieved through drainage of the abscess and intraperitoneal antibiotics.

Bacteriostatic Potential of Melatonin: Therapeutic Standing and Mechanistic Insights

“…Interestingly, melatonin facilitates H. pylori eradication in patients with gastroduodenal ulcer by omeprazole treatment ( 154 – 156 ), indicating melatonin can be used as an adjuvant clinical drug against H. Pylori infection. Furthermore, K. pneumonia is also a member of PGNB, isolated from the sputum of patients with pneumonia ( 157 ), mainly leads to pneumonia ( 158 ), septicemia ( 159 ) or bacteremia ( 160 ), meningitis ( 161 ) and peritonitis ( 162 ). An experimental study showed that the supply of 100 mg/kg of melatonin can reduce pro-inflammatory cytokines, inhibit microglial activation, and counteract neurocognitive damage in K. pneumoniae -infected rats ( 130 ).…”

Clinical and Molecular Characteristics and Antibacterial Strategies of Klebsiella pneumoniae in Pyogenic Infection

“…According to the most recent data from the China Antimicrobial Surveillance Network ( 13 ), K. pneumoniae accounted for 13.99% of all infections in a collection of 339,513 bacterial isolates from China in 2022. K. pneumoniae can cause pyogenic infections, such as pyogenic liver abscesses, skin, and soft tissue infections, including necrotizing fasciitis ( 19 , 20 ), abdominal and pelvic abscesses ( 2 ), renal abscesses ( 21 ), gallbladder abscesses ( 22 ), and lung abscesses ( 2 , 3 ). However, there is limited understanding regarding the molecular characteristics of this bacterium, the clinical features of the pyogenic infections it causes, and the molecular-clinical associations involved.…”

Splenic abscess diagnosed following relapsing sterile peritonitis in a peritoneal dialysis patient: A case report with literature review

“…We reviewed the relevant literature on PubMed for secondary peritonitis in PD patients since 2017 (Table 1). [8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23] Out of the 16 cases, perforation was the most common cause of secondary peritonitis, which might be easier to diagnose due to changes in dialysate properties. Two cases were complicated with abscesses in the kidney 8 and the spleen, as shown in our case, respectively.…”