Klebsiella pneumoniae Brain Abscess in Neonates: A Report of 2 Cases

Abstract

Brain abscesses are uncommon in neonates. Klebsiella pneumoniae is a very uncommon microbial agent to cause brain abscess. We report 2 infants with Klebsiella pneumoniae sepsis who developed brain abscesses. One infant was a premature neonate who required mechanical ventilation for respiratory distress syndrome and subsequently developed nosocomial sepsis and brain abscess without evidence of preceding meningitis. Another infant was a full-term neonate without risk factors for sepsis who developed seizures on the sixth postnatal day and was found to have meningitis and brain abscess. Both infants had Klebsiella pneumoniae septicemia with multiple relatively large brain abscesses that responded poorly to antimicrobial agents. These infants were managed with transfontanel drainage and prolonged courses of antimicrobial agents. Key message of this report is that Klebsiella pneumoniae brain abscess may occur in the absence of meningitis and even in the absence of any identifiable risk factors.

Multiple brain abscesses and facial palsy in a neonate

“…On follow-up, facial palsy improved and MRI repeated at 3 months of age showed resolution of abscesses. Brain abscess in a neonate with facial palsy has not been described previously 1–3. In our case, the likely aetiological agent is K pneumonia , even though CSF was sterile.…”

Coliforms Contamination in Raw Milk and Some Dairy Products with Special Reference to Comparative Identification of Enterobacter spp.

“…K. pneumoniae constitutes a part of the pneumonia-causing microorganisms worldwide [31]. K. oxytoca causes meningitis, severe neurological complications such as hydrocephaly, empyema, and brain abscesses [32]. The results in Table (3) revealed that E. aerogenes was confirmed by MALDI-TOF MS technique in 1 (100%) and 1 (33.3%) isolates out 1 and 3 of biochemically identified E. aerogenes isolates from raw milk and kariesh cheese, respectively.…”

Unusual Multiple Brain Abscesses Caused by Aeromonas hydrophila in a Preterm Neonate: Case Report

“…Brain abscess is one of the most critical complications of bacterial meningitis in neonates. 1 There are many bacterial pathogens reported to cause brain abscess.A. hydrophila has not been reported previously to cause brain abscess in neonates.…”