KDF1 promotes ameloblast differentiation by inhibiting the IKK/IκB/NF‐κB axis
Hangbo Liu,
Miao Yu,
Kai Sun
et al.
Abstract:Enamel protects teeth from external irritation and its formation involves sequential differentiation of ameloblasts, a dental epithelial cell. Keratinocyte differentiation factor 1 (KDF1) is important in the development of epithelial tissues and organs. However, the specific role of KDF1 in enamel formation and corresponding regulatory mechanisms are unclear. This study demonstrated that KDF1 was persistently expressed in all stages of ameloblast differentiation, through RNAscope in situ hybridization. KDF1 ex… Show more
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