Abstract:Anxiety and mood disorders are often comorbid with alcohol use disorder (AUD) and are considered critical in the development, maintenance, and reinstatement of alcohol dependence and harmful alcoholseeking behaviors. Because of this high comorbidity, it is necessary to determine shared and unique genetic factors driving heavy ethanol drinking and anxiety-related behaviors. We used a model of stressinduced escalation of drinking in ethanol dependent C57BL/6J mice to measure anxiety-like behaviors on the marble … Show more
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