<i>Incertae Sedis V. Aegyptianella</i>

Rikihisa, Yasuko; Kreier, Julius P.

doi:10.1002/9781118960608.gbm00907

Cited by 2 publications

(3 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Besides domestic fowl, Aegyptianella sp. has been linked to blood infections in lizards and frogs . However, the infection in frogs attributed to A ranarum involves a different vector (leech) rather than ticks, different internal shape, and sequences of the 16S rRNA (1310 bp) and gyrB (718 bp) genes most similar to those of Chryseobacterium meningosepticum , a bacterium in the family Flavobacteriaceae .…”

Section: Discussionmentioning

confidence: 99%

“…Infrequently, infectious agents such as haemogregarines, Haemoproteus sp., iridovirus, and Aegyptianella sp. have been documented with light microscopy within the erythrocytes of chelonians and other reptiles . In this report, we bring to attention the morphologic features of a newly recognized infectious inclusion within the erythrocytes of gopher tortoises belonging to the family Anaplasmataceae that resulted in clinical disease with a regenerative anemia…”

mentioning

confidence: 94%

See 1 more Smart Citation

Newly recognizedAnaplasmasp. in erythrocytes from Gopher Tortoises (Gopherus polyphemus)

Raskin

Crosby

Jacobson

2020

Veterinary Clinical Pathol

View full text Add to dashboard Cite

Background In 2015, a previously unrecognized intracytoplasmic erythrocytic inclusion was discovered in anemic wild‐caught adult gopher tortoises (Gopherus polyphemus). Subsequently, molecular diagnostics revealed this inclusion to be a novel Anaplasma sp. Objectives The goal of this study was to morphologically characterize these erythrocytic inclusions by light and transmission electron microscopy (TEM). Methods Blood samples were taken from two car‐injured wild‐caught gopher tortoises for the preparation of Wright‐Giemsa stained smears and TEM specimens. CBC data were serially performed and morphologically examined during treatment periods. Results Studies revealed a moderate to severe anemia with moderate regeneration as indicated by polychromasia and the presence of immature erythroid precursors. In addition, on light microscopy, one to two variably‐sized round basophilic stippled paracentral erythrocytic inclusions were present per cell in both animals and involved 10%‐25% of erythrocytes. TEM identified the intraerythrocytic inclusions as discrete membrane‐bound cytoplasmic vacuoles (morulae) containing membrane‐bound bacterial subunits that were of variable size, shape, and electron density. Serial hematologic data indicated complete remission of the infection in response to a single long‐term course of doxycycline. Conclusions The presence of a regenerative anemia in gopher tortoises from Florida revealed a newly recognized bacterial species that has morphologic characteristics similar to members of the genus Anaplasma.

show abstract

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 94%

Newly recognizedAnaplasmasp. in erythrocytes from Gopher Tortoises (Gopherus polyphemus)

Raskin

Crosby

Jacobson

2020

Veterinary Clinical Pathol

View full text Add to dashboard Cite

show abstract

“…pullorum from turkeys is closely related to Anaplasma [ 17 ], leading some authors to suggest that Ae. pullorum should be reclassified as an Anaplasma [ 18 , 19 ], but currently there is no consensus on this suggestion [ 20 ].…”

Section: Introductionmentioning

confidence: 99%

A novel candidate species of Anaplasma that infects avian erythrocytes

Vanstreels

Yabsley

Parsons³

et al. 2018

Parasites Vectors

View full text Add to dashboard Cite

BackgroundAnaplasma spp. are Gram-negative obligate intracellular bacteria transmitted by ticks. Even though numerous studies have detected DNA from Anaplasma spp. in the blood of birds, thus far mammals were the only vertebrates demonstrated to serve as competent hosts to these organisms. We report a novel candidate species of Anasplasma that was associated with cytoplasmic inclusions in the erythrocytes of an African penguin (Spheniscus demersus) in South Africa.MethodsCytoplasmic inclusions were morphologically characterized from freshly-produced blood smears, and phylogenetic analysis of 16S rRNA and groEL genes were used to evaluate the evolutionary relationships of the organism to other Anaplasmataceae.ResultsDark-purple round or oval inclusions consistent with Anaplasmataceae morulae were observed in the cytoplasm of erythrocytes. Phylogenetic trees produced using different methods agreed that the organism detected in this study belongs to the genus Anaplasma, and suggested that it is most closely related to the cluster comprising A. centrale, A. capra, A. marginale and A. ovis. We propose provisionally naming the strain detected in this study as “Candidatus Anaplasma sphenisci”.ConclusionsThis is the first species of Anaplasma shown to produce cytoplasmic inclusions in avian cells, opening the possibility that cytoplasmic inclusions in avian erythrocytes that had previously been attributed to Aegyptianella sp. might in fact correspond to Anaplasma. Further studies on the molecular biology of avian-infecting Anaplasmataceae will be valuable to provide insight into the evolution and epidemiology of these organisms.Electronic supplementary materialThe online version of this article (10.1186/s13071-018-3089-9) contains supplementary material, which is available to authorized users.

show abstract

Incertae Sedis V. Aegyptianella

Cited by 2 publications

References 13 publications

Newly recognizedAnaplasmasp. in erythrocytes from Gopher Tortoises (Gopherus polyphemus)

Newly recognizedAnaplasmasp. in erythrocytes from Gopher Tortoises (Gopherus polyphemus)

A novel candidate species of Anaplasma that infects avian erythrocytes

Contact Info

Product

Resources

About