1962
DOI: 10.1063/1.1717679
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In Vivo Oximeter with Fast Dynamic Response

Abstract: An in vivo oximeter which uses as a probe a standard cardiac catheter or a Cournand needle is described. The oxygen saturation is obtained from the light intensities at two wavelengths (805 and 660 m",) diffusely reflected by the unhemolyzed blood. The light is brought to the tip of the catheter and back again to the proximal end by means of glass fibers. Details of the construction of the instrument and experimental results are given. Drabkin and Schmidt. 8 E.

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Cited by 79 publications
(25 citation statements)
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“…The use of fiberoptics for oximetry began in the early 1960s (Polyani, 1960(Polyani, ,1962Enson, 1962;Kapany, 1967). Oxygen saturation measurements were made from blood in major vessels or the heart using catheterisation.…”
Section: In Vivo Methodsmentioning
confidence: 99%
“…The use of fiberoptics for oximetry began in the early 1960s (Polyani, 1960(Polyani, ,1962Enson, 1962;Kapany, 1967). Oxygen saturation measurements were made from blood in major vessels or the heart using catheterisation.…”
Section: In Vivo Methodsmentioning
confidence: 99%
“…These two bundles have been used as waveguides, one to guide the filtered light from a tungsten lamp source to the tip of the catheter, the other to guide the back-scattered and diffusely reflected light, modified in its spectral distribution due to blood interaction, into a photocell. The pulses of the source were located at 805 m and 660 m, to measure the oxygen saturation, and at 900 m and 805 m, to measure the dye concentration [23]. The reflected light has been analyzed spectrophotometrically, on the basis of the linear relationship between the measurand and the ratio of the intensities of the two reflected wavelengths [25].…”
Section: Earlier Intensity-modulated Configurationsmentioning
confidence: 99%
“…3). The innovative contribution of the system was its sensing probe, made of two glass fibers bundles located within a catheter (about 150 fibers with about 50 m in diameter each) [22][23][24]. These two bundles have been used as waveguides, one to guide the filtered light from a tungsten lamp source to the tip of the catheter, the other to guide the back-scattered and diffusely reflected light, modified in its spectral distribution due to blood interaction, into a photocell.…”
Section: Earlier Intensity-modulated Configurationsmentioning
confidence: 99%
“…[28][29][30][31][32][33][34][35][36][37][38][39][40][41][42] In the last years, their expansion has been benefiting from the development of telecommunications and OF communications, in particular, which are offering high-quality, miniaturized, and affordable optoelectronic components at competitive prices.…”
Section: 25mentioning
confidence: 99%