In VivoGenotoxicity and Cytotoxicity Kinetics of Trimethoprim Sulfamethoxazole in Well-nourished and Undernourished Young Rats
ROCÍO ORTIZ-MUÑIZ,
ELSA CERVANTES-RÍOS,
CATALINA SORIANO-CORREA
et al.
Abstract:Background/Aim: Undernutrition is a serious health problem prevalent in poor countries, affecting millions of people worldwide, especially young children, pregnant women, and sick elderly individuals. This condition increases vulnerability to infections, leading to widespread use of antibiotic treatments in undernourished populations. The objective of the present study was to determine the in vivo genotoxic and cytotoxic effects of trimethoprimsulfamethoxazole (TMP-SMX) treatment according to nutritional condi… Show more
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