In vivoanti-inflammatory effect of a sulfated polysaccharide isolated from the marine brown algaeLobophora variegata

Abstract

(2011) Invivo anti-inflammatory effect of a sulfated polysaccharide isolated from the marine brown algae Lobophoravariegata, Pharmaceutical Biology, 49:2, 167-174,

Antimicrobial effect of a crude sulfated polysaccharide from the red seaweed Gracilaria ornata

“…From this point of view, G. ornata SPs deserved further studies. These aspects are supported due to the use of this class of macromolecules in several economical fields (Farias et al 2000;Mazumder et al 2002;Duarte et al 2004;Pereira et al 2005;S.F-Tischer et al 2006;Araújo et al 2008;Siqueira et al 2011). The high cost of these polymers in the international market encourages to discover new natural sources of phycocolloids for biotechnology (Melo et al 2002;Maciel et al 2008;Campo et al 2009;Silva et al 2010).…”

“…The SPs yield and chemical and IR analyses varied among the differential extractions, with low values recorded at 25°C (Go-1) (Maciel et al 2008) when compared to those found at 80°C (Go-2 and Go-3) (Figs. 1 and 2, Table 1) (Amorim et al 2011), suggesting the occurrence, at least, of two "populations" of cell-wall SPs (Ray and Lahaye 1995;Rodrigues et al 2009;Graça et al 2011;Siqueira et al 2011), and that high temperature was an important parameter for G. ornata SPs extraction (Amorim et al 2011). (3,6-anhydrogalactose).…”

“…Some Gracilaria species have been reported as rich in SPs possessing antitumor (Fernández et al 1989), antiviral against herpes simplex virus types 1 and 2 (Mazumder et al 2002;Duarte et al 2004), and other with effects to minimize stress in cultured fishes (Araújo et al 2008). Although SPs modulate a large number of biological activities (Leite et al 1998;Ghosh et al 2004;Pereira et al 2005;Qi et al 2005;S.F-Tischer et al 2006;Fonseca et al 2008;Zhou et al 2004;Rodrigues et al 2009;Ananthi et al 2010;Sinha et al 2010;Graça et al 2011;Siqueira et al 2011), the antimicrobial activity has been rarely reported (Rao and Parekh 1981;Hellio et al 2001;Chotigeat et al 2004). From the red seaweed G. ornata, Leite et al (2005) purified and characterized a protein (lectin) that affected the development of cowpea weevil Callosobruchus maculates larvae.…”

Isolamento, fracionamento e avaliação toxicológica in vivo de polissacarídeos sulfatados de Hypnea musciformis

“…Segundo a revisão de CAMPO et al (2009), o uso de carragenanas degradadas como aditivos alimentares, quando testadas em modelos animais, induziram ulcerações intestinais e efeitos colaterais, sugerindo maiores os estudos sobre a utilização de PSs na dieta. Assim, estudos toxicológicos in vivo sobre PSs também contribuem para esse fim (LI et al, 2005;ASSREUY et al, 2008;LINS et al, 2009;SIQUEIRA et al, 2011).…”

Edematogenic activity of a sulfated galactan from the red marine algaeGelidium crinale

“…The literature has established an association between anti-inflammatory effects of fucans (Aruffo et al, 1991;Weston & Parish, 1991;Blondin et al, 1994;Tissot et al, 2003;Medeiros et al, 2008;Siqueira et al, 2011), the main representative sugar of brown algae (Phaeophyta), and proinflammatory/immunostimulant effects of galactans, the main representative sugar of red algae (Rodophyta). In this line, the sulfated polysaccharide obtained from the red seaweed Champia feldmannii DiazPifferer (Lomentariaceae) stimulated leukocyte migration and paw edema paralleled with increase in vascular permeability in rats (Assreuy et al, 2008) and antitumor effect in mice (Lins et al, 2009).…”