<i>In vitro</i> metabolism of HMTD and blood stability and toxicity of peroxide explosives (TATP and HMTD) in canines and humans

Gonsalves, Michelle; McLennan, Lindsay; Slitt, Angela L.; Smith, James L.; Oxley, Jimmie C.

doi:10.1080/00498254.2021.1874563

Cited by 3 publications

(2 citation statements)

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“…Oxley et al, interested metabolism of some peroxide explosives [128]. Triacetone triperoxide (TATP) and hexamethylene triperoxide diamine (HMTD) are prominent peroxide explosives.…”

Section: Hazardous Effects and Metabolismmentioning

confidence: 99%

Peroxide Based Organic Explosives

Türker

2021

EJCS

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In recent years progressively increasing terrorist activities, which use homemade explosives; such as acetone peroxide and other cyclic organic peroxides have led to worldwide awareness by security and defense agencies. Then the development of methodologies for the detection of cyclic organic peroxides have become an urgent need. Until quite recently, most of the current technology in use for trace detection of explosives had been unable to detect these energetic compounds. Differences in physical properties between cyclic organic peroxides is the main barrier for the development of a general method for analysis and detection of the peroxide explosives. In this short review, the most relevant contributions related to preparation, characterization and detection of the most important cyclic organic peroxides have been presented. It also includes few recent investigations about the toxicity and metabolism of some peroxide explosives.

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“…Oxley et al, interested metabolism of some peroxide explosives [128]. Triacetone triperoxide (TATP) and hexamethylene triperoxide diamine (HMTD) are prominent peroxide explosives.…”

Section: Hazardous Effects and Metabolismmentioning

confidence: 99%

Peroxide Based Organic Explosives

Türker

2021

EJCS

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“…Wierzbicki et al, performed some density functional calculations and X-ray investigations on P-and M-hexamethylene triperoxide diamine and its dialdehyde derivative [8]. Oxley and coworkers investigated decomposition, some reactions and some properties of HMTD [9][10][11][12][13]. Aernecke et al, developed a rapid method for vapor pressure measurement and used to derive the vapor pressure curve of the thermally labile peroxide-based explosive hexamethylene triperoxide diamine (HMTD) [14].…”

Section: Introductionmentioning

confidence: 99%

Some Ions of Hexamethylene Triperoxide Diamine - A DFT Treatment

Türker

2022

EJCS

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Hexamethylene triperoxide diamine (HMTD) is one of the peroxide type organic explosive which is sensitive to various stimuli including electrical charging. In the present study, within the restrictions of density functional theory at the level of B3LYP/6-311++G(d,p) some ionic forms of HMTD have been investigated. Its anionic and cationic forms considered all undergo decomposition. The monoanion form exhibited cleavage of two peroxide bonds and two C-H bonds whereas the monocation and dication forms show the rupture of O-CH2 bonds. Some quantum chemical properties and UV-VIS spectra of HMTD and the decomposed products were obtained and discussed.

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