<i>In vitro</i> efficacy of cefazolin and povidone‐iodine 5% in eradicating microbial organisms adhered to broad scleral buckles

Joseph, Joveeta; Pathengay, Avinash; Michael, Vincent; Raju, Biju; Sharma, Savitri; Das, Taraprasad

doi:10.1111/j.1442-9071.2006.01232.x

Cited by 8 publications

(3 citation statements)

References 8 publications

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“…The probable reason for this difference is the decline in usage of sponges in the last few decades. The scleral buckle infection rate was 0.2% compared to 0.5% to 5.6% in published literature [5,8,14-16]. …”

Section: Discussionmentioning

confidence: 90%

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Scleral buckle infections: microbiological spectrum and antimicrobial susceptibility

Chhablani

Nayak

Jindal

et al. 2013

J Ophthal Inflamm Infect

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BackgroundThe purpose of the present study was to evaluate the microbiological spectrum and antimicrobial susceptibility in patients with scleral buckle infection. Medical records of all the patients diagnosed as buckle infection at L. V. Prasad Eye Institute between July 1992 and June 2012 were reviewed in this non-comparative, consecutive, retrospective case series.FindingsA total of 132 eyes of 132 patients underwent buckle explantation for buckle infection during the study period. The incidence of buckle infection at our institute during the study period was 0.2% (31 out of 15,022). A total of 124 isolates were identified from 102 positive cultures. The most common etiological agent isolated was Staphylococcus epidermidis (27/124, 21.77%) followed by Mycobacterium sp. (20/124, 16.13%) and Corynebacterium sp. (13/124, 10.48%). The most common gram negative bacilli identified was Pseudomonas aeruginosa (9/124, 7.26%). The median interval between scleral buckling surgery and onset of symptoms of local infection was 30 days. All eyes underwent buckle explantation and median time interval between primary SB surgery and explantation was 13 months. Recurrent retinal detachment was observed in two cases at 7 and 48 months, respectively, after buckle explantation. Gram positive, gram negative, and acid-fast organisms isolated from 2003 to 2012 were most commonly susceptible to vancomycin (100%), ciprofloxacin (100%), and amikacin (89%). Susceptibility to ciprofloxacin during the same time period was observed in 75% (15/20), 100% (13/13), and 87% (7/8) of gram positive, gram negative, and acid-fast isolates, respectively.ConclusionScleral buckle infection is relatively rare and has a delayed clinical presentation. It is most commonly caused by gram positive cocci. Based on the current antimicrobial susceptibility, ciprofloxacin can be used as empirical therapy in the management of scleral buckle infections.

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Section: Discussionmentioning

confidence: 90%

“…Buckle infection is one of the common causes for buckle explantation. The reported incidence of buckle infection varies from 0.5% to 5.6% [5,8,14-16]. Buckle infection may lead to severe complications like endophthalmitis and panophthalmitis [2].…”

Section: Resultsmentioning

confidence: 99%

Scleral buckle infections: microbiological spectrum and antimicrobial susceptibility

Chhablani

Nayak

Jindal

et al. 2013

J Ophthal Inflamm Infect

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“…Their estimated incidence varies from 0.2% to 5.6%. [23456] Coagulase-positive and coagulase-negative Staphylococci are implicated as the most common organisms causing SB infection (70%–90% of cases). [6] However, rarer cases with infections due to atypical mycobacterium, corynebacteria, and fungi have been reported.…”

Section: Discussionmentioning

confidence: 99%

Scleral buckle infection by Serratia species

et al. 2017

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We describe a rare case of scleral buckle (SB) infection with Serratia species. A 48-year-old male with a history of retinal detachment repair with scleral buckling presented with redness, pain, and purulent discharge in the left eye for 4 days. Conjunctival erosion with exposure of the SB and scleral thinning was noted. The SB was removed and sent for culture. Blood and chocolate agar grew Gram-negative rod-shaped bacillus identified as Serratia marcescens. On the basis of the susceptibility test results, the patient was treated with oral and topical antibiotics. After 6 weeks of the treatment, his infection resolved.

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Prophylaxis for acute scleral buckle infection using 0.25 % povidone-iodine ocular surface irrigation during surgery

et al. 2013

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To investigate whether repeated washing of the ocular surface with 0.25 % povidone-iodine during scleral buckling surgery minimizes ocular surface bacterial contamination at completion of the procedure. A total of 489 consecutive eyes that underwent scleral buckling at a single institution were categorized into two groups according to the intraoperative ocular surface washing method used during two separate time periods--a group using physiological saline (saline group, 222 consecutive eyes) and a group using 0.25 % povidone-iodine (PI group 267, consecutive eyes). In 37 eyes of each group, ocular surface fluids were sampled at the beginning of surgery and at completion of buckling, and subjected to bacteriological culture. Acute scleral buckle infection occurred in one patient, and was caused by Pseudomonas aeruginosa. The incidence of acute scleral buckle infection was 0.45 % (1/222 eyes) in the saline group, and 0 % in the PI group, with no significant difference (P = 0.4540). The bacterial detection rates in ocular surface fluid at the beginning of surgery were 5.4 % (2/37 eyes) using saline and 8.1 % (3/37 eyes) using povidone-iodine, with no significant difference (P = 0.6433). The rates at completion of buckling were 18.9 % (7/37 eyes) using saline and 0 % (0 eye) using povidone-iodine, with a significant difference (P = 0.0114). Repeated washing of the ocular surface with 0.25 % povidone-iodine during scleral buckling procedure reduced the ocular surface bacterial contamination rate to an extremely low level at completion of buckling, suggesting that this method is useful for the prevention of acute scleral buckle infection.

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In vitro efficacy of cefazolin and povidone‐iodine 5% in eradicating microbial organisms adhered to broad scleral buckles

Cited by 8 publications

References 8 publications

Scleral buckle infections: microbiological spectrum and antimicrobial susceptibility

Scleral buckle infections: microbiological spectrum and antimicrobial susceptibility

Scleral buckle infection by Serratia species

Prophylaxis for acute scleral buckle infection using 0.25 % povidone-iodine ocular surface irrigation during surgery

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