<i>In vitro</i> cytotoxic activity of <i>Cuphea ingrata</i> Cham. &amp; Schltdl. extracts related to the oenothein B content

Sobolewska, Danuta; Galanty, Agnieszka; Granica, Sebastian; Podolak, Irma; Olszewska, Monika A.; Owczarek, Aleksandra; Paulino, Niraldo; Michalska, Klaudia

doi:10.1080/14786419.2022.2103699

Cited by 2 publications

(2 citation statements)

References 12 publications

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“…Polyphenol rich n -butanol and ethyl acetate fractions, obtained from the methanolic extract of the aerial parts of C. ingrata , showed cytotoxic effects in several human melanoma cell lines (A375, HTB-140, WM793) [ 127 ]. It should be noted that their effect on highly metastatic HTB-140 melanoma cells was greater compared to doxorubicin.…”

Section: Pharmacological Activity Of Cuphea Plants...mentioning

confidence: 99%

The Genus Cuphea P. Browne as a Source of Biologically Active Phytochemicals for Pharmaceutical Application and Beyond—A Review

Sobolewska

Michalska

Wróbel‐Biedrawa

et al. 2023

IJMS

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Cuphea P. Browne (Lythraceae) is a monophyletic taxon comprising some 240–260 species that grow wild in the warm, temperate, and tropical regions of South and Central America and the southern part of North America. They have been valued as traditional medicinal remedies for numerous indications, including treating wounds, parasitic infections, hypertension, digestive disorders, cough, rheumatism, and pain. Modern pharmacological research provides data that support many of these traditional uses. Such a wide array of medicinal applications may be due to the exceptionally rich phytochemical profile of these plants, which includes bioactive compounds classified into various metabolite groups, such as polyphenols, triterpenes, alkaloids, and coumarins. Furthermore, Cuphea seed oils, containing medium-chain fatty acids, are of increasing interest in various industries as potential substitutes for coconut and palm oils. This review aims to summarize the results of phytochemical and pharmacological studies on Cuphea plants, with a particular focus on the therapeutic potential and molecular mechanisms of the action of polyphenolic compounds (especially flavonoids and tannins), which have been the subject of many recently published articles.

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Section: Pharmacological Activity Of Cuphea Plants...mentioning

confidence: 99%

The Genus Cuphea P. Browne as a Source of Biologically Active Phytochemicals for Pharmaceutical Application and Beyond—A Review

Sobolewska

Michalska

Wróbel‐Biedrawa

et al. 2023

IJMS

Self Cite

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“…This compound represents about 4-8% of the dry mass of herb depending on season, harvest time, plant organ, or genotype [35][36][37][38]. Oenothein B showed a broad spectrum of pharmacological properties including antioxidant, anti-cancer, anti-androgen, immunostimulatory, metal binding, and antimicrobial activities [39][40][41]. Apart from oenothein B, other ellagitannins from monomeric up to heptamers (e.g., tellimagrandin I, II, woodfordin, oenothein A, and others) were identified in E. angustifolium plants [42].…”

Section: Introductionmentioning

confidence: 99%

Antibacterial and Antimycotic Activity of Epilobium angustifolium L. Extracts: A Review

Dreger,

Adamczak,

Foksowicz-Flaczyk

2023

Pharmaceuticals

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The aim of this work was to provide an overview of available information on the antibacterial and antifungal properties of Epilobium angustifolium extracts. A literature search of Scopus, PubMed/Medline, and Google Scholar for peer-reviewed articles published between January 2000 and June 2023 was undertaken. A total of 23 studies were eligible for inclusion in this review. Significant variation of antimicrobial activity depending on the tested species and strains, type of extract solvent, or plant organs utilized for the extract preparation was found. E. angustifolium extracts were active against both Gram-positive and Gram-negative bacteria and showed antimycotic effects against the fungi of Microsporum canis and Trichophyton tonsurans and the dermatophytes Arthroderma spp. Greater susceptibility of Gram-positive than Gram-negative bacteria to fireweed extracts was found. A strong antibacterial effect was recorded for Staphylococcus aureus, Bacillus cereus, Micrococcus luteus, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter baumannii including multi-drug resistant strains. E. angustifolium extract might find practical application as an antimicrobial in wound healing, components of cosmetic products for human and animals, or as food preservatives.

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In vitro cytotoxic activity of Cuphea ingrata Cham. & Schltdl. extracts related to the oenothein B content

Cited by 2 publications

References 12 publications

The Genus Cuphea P. Browne as a Source of Biologically Active Phytochemicals for Pharmaceutical Application and Beyond—A Review

The Genus Cuphea P. Browne as a Source of Biologically Active Phytochemicals for Pharmaceutical Application and Beyond—A Review

Antibacterial and Antimycotic Activity of Epilobium angustifolium L. Extracts: A Review

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