<i>In vitro</i>Cyto and Blood Compatibility of Titanium Containing Diamond-Like Carbon Prepared by Hybrid Sputtering Method

Pandiyaraj, K. Navaneetha; Heeg, Jan; Lampka, Andreas; Junge, Fabian; Barfels, T.; Wienecke, M.; Rhee, Young Ha; Kim, Hyung Woo

doi:10.1088/1009-0630/14/9/11

Cited by 21 publications

(15 citation statements)

References 26 publications

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“…The C1s spectra were deconvoluted by Gauss‐Lorentz curves, corresponding to the peaks of C–Ti (only in case of the carbon‐titanium composite layers), C‐Si, sp 2 phase, sp phase, C‐O, and C=O bounds. Obtained peak maxima were around 281.9 eV, 284.2 eV, 284.5 eV, 285.3 eV, 286.1 eV, 288 eV, respectively …”

Section: Methodsmentioning

confidence: 96%

Effect of plasma treatment on the surface properties of polydimethylsiloxane

Kaczorowski

Szymański

Batory

et al. 2014

J of Applied Polymer Sci

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In this work, the analysis of the plasma modification of polydimethylsiloxane (PDMS) substrates was conducted. The influence of the modification onto the changes occurred within the geometrical structure and chemical composition of the surface was analyzed. Due to the study of the atomic force microscopy, it was possible to determine the relationships between the surface development and applied process parameters, defining the conditions facilitating to obtain isotropic or anisotropic orientations of wrinkles. A precise analysis of the chemical composition of the surface, executed before and after the modification processes, enabled to define the changes in their elementary composition. Moreover, the modification influence onto the changes of the contact angle and the surface free energy were also analyzed. So, based on the research it was stated that the increase of value of the surface free energy is proportional to the sp 3 phase contents in the DLC coatings.

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Section: Methodsmentioning

confidence: 96%

Effect of plasma treatment on the surface properties of polydimethylsiloxane

Kaczorowski

Szymański

Batory

et al. 2014

J of Applied Polymer Sci

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“…The increased thromboresistivity of DLC films deposited by the radio frequency plasma enhanced CVD method and treated with plasma of oxygen gas has been discussed in [86]. The experiments show the strong dependency of DLC properties on the deposition conditions and doping effects [80,[87][88][89]. The results concerning in vivo testing and medical studies of DLC coated stents can be found in several papers [80,[90][91][92].…”

Section: Diamond-like Carbon (Dlc) Coatingsmentioning

confidence: 99%

Recent Advances in Manufacturing Innovative Stents

et al. 2020

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Cardiovascular diseases are the most distributed cause of death worldwide. Stenting of arteries as a percutaneous transluminal angioplasty procedure became a promising minimally invasive therapy based on re-opening narrowed arteries by stent insertion. In order to improve and optimize this method, many research groups are focusing on designing new or improving existent stents. Since the beginning of the stent development in 1986, starting with bare-metal stents (BMS), these devices have been continuously enhanced by applying new materials, developing stent coatings based on inorganic and organic compounds including drugs, nanoparticles or biological components such as genes and cells, as well as adapting stent designs with different fabrication technologies. Drug eluting stents (DES) have been developed to overcome the main shortcomings of BMS or coated stents. Coatings are mainly applied to control biocompatibility, degradation rate, protein adsorption, and allow adequate endothelialization in order to ensure better clinical outcome of BMS, reducing restenosis and thrombosis. As coating materials (i) organic polymers: polyurethanes, poly(ε-caprolactone), styrene-b-isobutylene-b-styrene, polyhydroxybutyrates, poly(lactide-co-glycolide), and phosphoryl choline; (ii) biological components: vascular endothelial growth factor (VEGF) and anti-CD34 antibody and (iii) inorganic coatings: noble metals, wide class of oxides, nitrides, silicide and carbide, hydroxyapatite, diamond-like carbon, and others are used. DES were developed to reduce the tissue hyperplasia and in-stent restenosis utilizing antiproliferative substances like paclitaxel, limus (siro-, zotaro-, evero-, bio-, amphi-, tacro-limus), ABT-578, tyrphostin AGL-2043, genes, etc. The innovative solutions aim at overcoming the main limitations of the stent technology, such as in-stent restenosis and stent thrombosis, while maintaining the prime requirements on biocompatibility, biodegradability, and mechanical behavior. This paper provides an overview of the existing stent types, their functionality, materials, and manufacturing conditions demonstrating the still huge potential for the development of promising stent solutions.

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“…For example, they have been widely used in packaging, furniture, toys, automobiles, food and beverage containers, biomedical implants, and solar power devices. Among polymers, Polyethylene terephthalate (PET) holds diverse applications as cardiovascular implants (artificial heart valves and blood vessels), food and beverage containers, and components in solar cells [1][2][3]. PET is a semicrystalline polymer with a simple long chain belong to polyester family and possesses outstanding properties like chemical inertness, high mechanical strength, toughness, and fatigue resistance.…”

Section: Motivationsmentioning

confidence: 99%

“…These materials range from diamonds that have super high hardness and extremely high thermal conductivity, to graphite, which is very soft and can be used as a solid lubricant. Carbon has the ability to be in three different electronic configurations, sp 1 , sp 2 and sp 3 , which is the source of its unique behaviors [16]. Carbon has six electrons, which are configured as 1s 2 2s 2 2p 2 and illustrated in The electron distribution of carbon makes it possible to form different allotropes with three bonding configurations, as well as the ability to form single, double and triple bonds.…”

Section: Carbon Materialsmentioning

confidence: 99%

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Fabrication and characterization of adherent diamond-like carbon based thin films on polyethylene terephthalate by end hall ion beam deposition

Ashtijoo

Bhattacherjee

Sutarto

et al. 2016

Surface and Coatings Technology

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The application of Polyethylene terephthalate (PET) has been steadily increasing during recent years. However, its low wear resistance, high gas permeation rate and poor biocompatibility have significantly limited its applications in some specific areas. On the contrary, diamond-like carbon (DLC) possesses many unique properties such as the high hardness, low friction coefficient, high transparency, good gas barrier, excellent biocompatibility, and low synthesis temperature, which makes it an ideal coating material for modifying the surfaces of PET for applications as food and beverage containers and biomedical implants. Nevertheless, the adhesion of DLC on PET is poor due to the high stress induced by ion bombardment during DLC deposition and the large mechanical property mismatch between the coating and the substrate. Therefore, it is very important to develop techniques to lower the stress of DLC and to enhance the adhesion strength of DLC to PET.In the present thesis work, low energy end-hall (EH) ion source and element (N and Si) doping were used to deposit DLC to lower its internal stress and ion beam treatment was performed to modify the surface of PET to enhance the adhesion between DLC and PET. In addition, two different hydrocarbon gases (CH 4 and C 2 H 2 ) were used as precursors for DLC deposition in order to understand the effect of precursor gas. The structure and properties of the treated PET and deposited DLC films were characterized by various advanced techniques: The adhesion of DLC to PET was assessed using scratch testing; the composition and bonding states of DLC and treated PET were analyzed by Raman spectroscopy, Fourier transform infrared spectroscopy (FTIR), X-ray photoelectron spectroscopy (XPS), and near edge X-ray absorption fine structure (NEXAFS); the hardness and Young's modulus were measured by nano-indentation; the tribological properties of the coated materials were evaluated by pin-on-disk sliding testing; and the surface tomography and surface roughness were investigated by atomic force microscopy and N forms sp 3 C-N and sp 2 C=N bonds in the films. Consequently, the hardness values decrease from 11.5 GPa for pure DLC to 7.0 GPa for N-DLC samples whereas the hardness of Si-DLC increases with increasing the silicon content. In addition, N doping can reduce residual stress of DLC and thus increases adhesion of DLC. The DLC films deposited using methane show better properties than using acetylene. By optimizing the conditions, dense, smooth, and adhesive DLC films have been deposited onto PET using EH ion source by combining N doping and O ion treatment with methane as precursor gas.iv AKNOWLEDGEMENTS

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In vitroCyto and Blood Compatibility of Titanium Containing Diamond-Like Carbon Prepared by Hybrid Sputtering Method

Cited by 21 publications

References 26 publications

Effect of plasma treatment on the surface properties of polydimethylsiloxane

Effect of plasma treatment on the surface properties of polydimethylsiloxane

Recent Advances in Manufacturing Innovative Stents

Fabrication and characterization of adherent diamond-like carbon based thin films on polyethylene terephthalate by end hall ion beam deposition

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