In‐Vitro Comparison of the Larvicidal Activity of Moxidectin and Abamectin Against Onthophagus gazella (F.) (Coleoptera: Scarabaeidae) and Haematobia irritans exigua De Meijere (Diptera: Muscidae)

Doherty, W.M; Stewart, N. P.; Cobb, R. M.; Keiran, P. J.

doi:10.1111/j.1440-6055.1994.tb00924.x

Cited by 41 publications

(57 citation statements)

References 15 publications

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“…The fertility and the adult emergence rate decreased, whereas the mortality of newly hatched adults and the mortality of larvae could be important. This was demonstrated for several dung beetle species such as Onthophagus, Euoniticellus, Copris, Onitis and Aphodius genera [4,13,14,17,22,24].…”

Section: Discussionmentioning

confidence: 81%

The negative effects of the residues of ivermectin in cattle dung using a sustained-release bolus on Aphodius constans (Duft.) (Coleoptera: Aphodiidae)

et al. 2001

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-This paper reports the findings of two trials into the effects of the treatment of cattle with ivermectin slow-release (SR) bolus on the larval development of the dung beetle Aphodius constans Duft. Rectal faecal samples were collected prior to treatment and every 3 and 2 weeks in a first and second trial, respectively, and up to 156 days post-administration of the SR bolus. Faecal ivermectin concentration reached a peak at 63 days post-treatment (1427 ng⋅g -1 ) and ivermectin was detected up to 147 days post-treatment in the first trial (7.2 ng⋅g -1 ). First stage larvae of A. constans were reared with control or contaminated dung and adult beetles were counted after emergence. In the first trial, the comparison of pairwise samples showed that ivermectin prevented the development of larval A. constans until day 105, while at day 135 the rate of emergence was still significantly lower than the corresponding series of control (p < 0.05). In the second trial, the difference between control and treated series remained significant until 143 days post-treatment, with no emergence until 128 days post-administration of SR bolus to cattle. These results show the negative effect of ivermectin on the development of larval A. constans, even at a low concentration (38.4 ng⋅g -1 ). The administration of ivermectin sustained-release bolus to cattle was highly effective in killing dung beetle larvae for approximately 143 days after treatment. The results were similar when dung was obtained from a single animal kept alone, or from a blending of faecal pats obtained from a group of animals kept in field conditions during the whole trial period.ivermectin / sustained-release (SR) bolus / cattle / dung beetle / rate of emergence / environmental risk Vet. Res. 32 (2001) [421][422][423][424][425][426][427] 421

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Section: Discussionmentioning

confidence: 81%

The negative effects of the residues of ivermectin in cattle dung using a sustained-release bolus on Aphodius constans (Duft.) (Coleoptera: Aphodiidae)

et al. 2001

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“…in dung from moxidectin-treated cattle. When Doherty et al (1994) investigated the effects of ivermectin and moxidectin directly added to the dung of cattle on the growth of O. gazella larvae, ivermectin at 0.008 ppm inhibited adult emergence by 95% and at 0.016 ppm by 100%, while, moxidectin at 0.512, 0.256, 0.008, and 0.016 ppm inhibited adult emergence by 93, 39, 19, and 11%, respectively. Since no effect of moxidectin was observed in adult emergence rates of Caccobius jessoensis (in control and treated groups on any date of the first or second trial in the laboratory), and since fecal moxidectin residue reached a level of 0.95 ppm, perhaps the tolerance of C. jessoensis to moxidectin is equivalent to or larger than that of O. gazella.…”

Section: Discussionmentioning

confidence: 99%

Effects of moxidectin on coprophagous insects in cattle dung pats in Japan

Iwasa

Suzuki

Maruyama

2008

Appl. Entomol. Zool.

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Effects of the antiparasitic drug moxidectin were studied in laboratory and field experiments in Hokkaido, Japan by pour-on administrations (500 mg/kg) on a target pest Haematobia irritans Linnaeus, nontarget coprophagous flies represented by Neomyia cornicina (Fabricius), and the dung beetle Caccobius jessoensis Harold. The concentration of moxidectin excreted into cattle dung was maximum at 3 days post-treatment both in the first and second trials, and then it diminished. No moxidectin was detected on or after day 21 post-treatment in the first trial, and on or after day 28 post-treatment in the second trial. Larval development of H. irritans was hampered from 1 to 7 days post-treatment. No N. cornicina pupated in dung at days 1 and 3 post-treatment, and pupation and emergence rates were reduced in the dung until 7 days post-treatment. There were no significant differences in numbers and weight of brood balls constructed by Caccobius jessoensis in dung from treated and control cattle. Adult emergence rates of C. jessoensis on days 1, 3, 7, 14 post-treatments were not significantly different between control and treated groups, and more than 90% of adult emergence rates were demonstrated in both groups. In the field study using emergence traps, 3,433 (18 families) flies emerged from dung from untreated control cattle and 1,667 (16 families) flies emerged from dung from treated cattle. Notably, the number of Sciaridae spp. (first Experiment) and Sepsis latiforceps Duda and Sphaeroceridae spp. (second Experiment) significantly decreased in dung pats of treated cattle. From 48 dung pats in the field experiments, total dry weight of major coprophagous flies that emerged was 1,741.8 mg in dung from control cattle and 1,170.0 mg in dung from treated cattle, showing 32.8% reduction in treated dung. Emergence rates of C. jessoensis from brood balls recovered from soil beneath dung pats in the field experiments were not significantly different between dung from control and treated cattle on each sampling day (1, 7, 14, and 21 days) post-treatment.

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“…However, macrocyclic lactones including moxidectin, a milbemycin, seem to be less harmful to arthropods than ivermectin [11]. Moxidectin is less toxic to Onthophagus gazella and Haematobia irritans exigua than abamectin and a 64-fold higher concentration of moxidectin than abamectin is required to produce similar toxicity [7]. Strong and Wall [24] did not find differences between dung fauna colonisation from moxidectin-injected cattle and controls.…”

Section: Differences Between Endectocides For Residue Toxicitymentioning

confidence: 87%

Helminthic control on grazing ruminants and environmental risks in South America

Suárez¹

2002

Vet. Res.

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-The control of ruminant gastrointestinal nematodes and ectoparasites, one of the major production health problems, are heavily reliant on the systematic and sometimes abusive use of anthelmintic drugs. Endectocides are the most frequently used drugs, having high potency against arthropods and nematodes. Their dung pat residues enhance the risk of adverse effects on non-target invertebrates and on the general grazing cattle ecosystem. In this scenario, our objective is to review current knowledge of the agro-environmental and biodiversity impact and risks of endectocides in South America. The effects of faecal drug residues of ivermectin and doramectin on dung colonising invertebrates and dung degradation have been reported in studies carried out in the temperate centre of Argentina and in the subtropical region of Brazil. The results from Argentina showed a depression in invertebrate colonisation and degradation of dung recovered from endectocide treated cattle during the autumn. Comparisons have shown that ivermectin and doramectin have similar adverse effects. A decrease of Coleoptera larvae, Diptera larvae, Staphylinidae, Collembola, Acari and dung specific nematodes was noted in pats from both endectocides. The results from Brazil showed that dipterous larvae, Polyphaga coleopteran larvae and adults and mites were significantly reduced in the ivermectin treated group. The disturbances that macrocyclic lactones can produce on non-targeted invertebrates and on their associated participation in dung degradation and soil element recycling, are unpredictable and can negatively influence biodiversity and the agricultural ecosystem sustainability.endectocide / environmental risk / South America / cattle grazing system / dung fauna Résumé -Contrôle des helminthes chez les ruminants à l'herbe et risques environnementaux en Amérique du Sud. Le contrôle des nématodes gastro-intestinaux et des ectoparasites, qui est l'un des problèmes de santé majeurs dans la production bovine, repose largement sur l'utilisation systé-matique et parfois abusive d'anthelmintiques. Les endectocides, qui ont un effet puissant contre les arthropodes et les nématodes, sont les médicaments le plus fréquemment utilisés. Leurs résidus dans les matières fécales augmentent les risques d'effets nocifs sur des invertébrés qui ne sont pas la cible 563

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In‐Vitro Comparison of the Larvicidal Activity of Moxidectin and Abamectin Against Onthophagus gazella (F.) (Coleoptera: Scarabaeidae) and Haematobia irritans exigua De Meijere (Diptera: Muscidae)

Cited by 41 publications

References 15 publications

The negative effects of the residues of ivermectin in cattle dung using a sustained-release bolus on Aphodius constans (Duft.) (Coleoptera: Aphodiidae)

The negative effects of the residues of ivermectin in cattle dung using a sustained-release bolus on Aphodius constans (Duft.) (Coleoptera: Aphodiidae)

Effects of moxidectin on coprophagous insects in cattle dung pats in Japan

Helminthic control on grazing ruminants and environmental risks in South America

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