In vitro comparative evaluation of Tamarix gallica extracts for antioxidant and antidiabetic activity

Abstract

Tamarix gallica known as Jhau is traditionally used as expectorant, liver tonic, laxative, astringent, and antidiarrheal. The current study was proposed to determine the in vitro antioxidant, antidiabetic properties of the methanolic, ethanolic, and aqueous extracts of Tamarix gallica arial part, subsequently the phytochemical evaluation. Hence, Tamarix gallica arial part extracts were extracted with methanol (MthTg), ethanol (EthTg), and distilled water (AqTg). Extracts phytochemical analysis were accomplished to identify the phenolic components (TPC and TFC). Extracts antioxidant property was evaluated by DPPH, FRAP, and ABTS assay. For antidiabetic property, α-amylase and α-glucosidase inhibitory activities were assessed. One Way ANOVA was applied statistically by means of software SPSS Statistics 23 and attained data were definite as mean ± standard deviation. Result revealed that EthTg have the maximum TPC and TFC levels than MthTg and AqTg. Antioxidant property in relations of DPPH (lowest IC50 = 1.309 ± 0.31), FRAP (323.51 ± 2.32), and ABTS (266.97 ± 25.14) assay was also highest in EthTg. EthTg was also exposed highest α-amylase and α-glucosidase inhibition activity with lower IC50 (1.116 ± 0.051; 0.402 ± 0.2, respectively). The extracts antioxidant and antidiabetic activities order was as EthTg > MthTg > AqTg. TFC and TPC also revealed directly proportional correlation with antioxidant, and antidiabetic properties of the Tamarix gallica arial part extracts. Results noticeably stated that the ethanolic extract of Tamarix gallica have the highest antioxidant and antidiabetic properties. Tamarix gallica has competency to reduce the oxidative stress and can be utilized in the management of diabetes.

Rowanberry—A Source of Bioactive Compounds and Their Biopharmaceutical Properties

“…Recent studies show the direct connection between the antioxidant activity of various plant extracts and the antitumor [ 68 , 69 ], antidiabetic [ 70 , 71 , 72 ] and antibacterial [ 73 , 74 , 75 ] activities.…”

Uncovering chemical profiles, biological potentials, and protection effect against ECM destruction in H2O2‐treated HDF cells of the extracts of Stachys tundjeliensis

“…Indeed, a number of studies have observed the positive correlation between TPC/TFC and the antioxidant efficacy of plant extracts. [ 24–27 ] It is to be noted that a number of previous studies have also evidenced the antioxidant properties of other Stachys species. For instance, promising antiradical effect (1.9–17.3 mg TE/g dry plant) and metal ion reducing power (4.6–14.6 mg TE/g dry plant) was recorded by S. cretica subsp.…”

“…Indeed, a number of studies have observed the positive correlation between TPC/TFC and the antioxidant efficacy of plant extracts. [24][25][26][27] It is to be noted that a number of previous studies have also evidenced the antioxidant properties of other Stachys species.…”

“…Compounds 24-28, 29, 31, 36, 39, and 40 gave fragment ions, corresponding to the loss of a hexose (−162.05 Da), together with fragments from the deprotonated caffeic (24,25,36), coumaric (26,29,39,40), and ferulic acids (26,27) at m/z 179.0304, 163.0388, and 193.0495, respectively. MS/MS spectra of sugar esters caffeoylhexose (25) and feruloyl-hexose (28) were acquired.…”