<i>In vitro</i> bioactivity study of <scp>TiCaPCO(N)</scp> and Ag‐doped <scp>TiCaPCO(N)</scp> films in simulated body fluid

Сухорукова, И. В.; Sheveyko, A.N.; Kiryukhantsev‐Korneev, Ph. V.; Левашов, Е. А.; Shtansky, Dmitry V.

doi:10.1002/jbm.b.33534

Cited by 10 publications

(8 citation statements)

References 67 publications

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“…The coating material with both antimicrobial activity and biocompatibility is important and leads to enhancement of the probability of implant success [ 9 ]. The following functionalization strategies have already been applied to increase antibacterial potential: drug-loaded surfaces [ 10 ], silver-implanted surfaces [ 11 ], polymer-functionalized surfaces [ 12 ], anodized/oxidized/ion-implanted surfaces [ 13 , 14 ], UV-activated surfaces [ 15 ], nanoscale surfaces [ 16 ], etc. A systematic review by J. Grischke et al concluded that highly modified surfaces enhance antimicrobial activity compared to that of commercial, pure titanium [ 8 ], but some research proved the significant cell toxicity of these surfaces [ 17 , 18 ], which limits the clinical application of new surfaces.…”

Section: Introductionmentioning

confidence: 99%

In Vitro Biological Characterization of Silver-Doped Anodic Oxide Coating on Titanium

et al. 2020

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Despite the high biocompatibility and clinical effectiveness of Ti-based implants, surface functionalization (with complex osteointegrative/antibacterial strategies) is still required. To enhance the dental implant surface and to provide additional osteoinductive and antibacterial properties, plasma electrolytic oxidation of a pure Ti was performed using a nitrilotriacetic acid (NTA)-based Ag nanoparticles (AgNP)-loaded calcium–phosphate solution. Chemical and structural properties of the surface-modified titanium were assessed using scanning electron microscopy (SEM) with energy dispersive X-ray (EDX) and contact angle measurement. A bacterial adhesion test and cell culture biocompatibility with collagen production were performed to evaluate biological effectiveness of the Ti after the plasma electrolytic process. The NTA-based calcium–phosphate solution with Ag nanoparticles (AgNPs) can provide formation of a thick, porous plasma electrolytic oxidation (PEO) layer enriched in silver oxide. Voltage elevation leads to increased porosity and a hydrophilic nature of the newly formed ceramic coating. The silver-enriched PEO layer exhibits an effective antibacterial effect with high biocompatibility and increased collagen production that could be an effective complex strategy for dental and orthopedic implant development.

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Section: Introductionmentioning

confidence: 99%

In Vitro Biological Characterization of Silver-Doped Anodic Oxide Coating on Titanium

et al. 2020

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“…The obtained results agree well with those previously reported for multicomponent TiCaPCON-based bioactive surfaces. 54 …”

Section: Resultsmentioning

confidence: 99%

Characteristics and in vitro response of thin hydroxyapatite–titania films produced by plasma electrolytic oxidation of Ti alloys in electrolytes with particle additions

et al. 2016

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“…Nevertheless, the ESA method has a number of disadvantages, such as a high content of structural defects (pores, microcracks) [8], high level of surface roughness [9], in some cases, contamination by oxygen (for example, if the process was conducted in an air environment), and the presence of substrate matter in the coating composition [10].…”

Section: Introductionmentioning

confidence: 99%

Two-Layer Nanocomposite TiC-Based Coatings Produced by a Combination of Pulsed Cathodic Arc Evaporation and Vacuum Electro-Spark Alloying

Kiryukhantsev-Korneev

Сытченко

Sheveyko

et al. 2020

Materials

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A novel two-stage technology combining vacuum electro-spark alloying (VESA) and pulsed cathodic arc evaporation (PCAE) was approbated for the deposition of TiC-based coatings in inert (Ar) and reactive (C2H4) atmospheres. The deposition was carried out using a TiC-NiCr-Eu2O3 electrode and 5140 steel substrates. Structural, elemental, and phase compositions of the deposited coatings were investigated by scanning electron microscopy, energy-dispersive spectrometry, and X-ray diffraction. The mechanical properties of the coatings were measured by nanoindentation using a 4 mN load. The tribological properties of the coatings were measured using the pin-on-disc setup in air and in distilled water at a 5 N load. The experimental data suggest that VESA coatings are characterized by surface defects, a hardness of 12.2 GPa, and a friction coefficient of 0.4. To ensure good adhesion between the VESA coating and the upper layer containing diamond-like carbon (DLC), an intermediate layer was deposited by PCAE in the Ar atmosphere. The intermediate layer had a hardness of up to 31 GPa. The upper layer of the coating ensured a low and stable friction coefficient of 0.2 and high wear resistance due to the formation of an sp2–sp3 bound carbon phase. Multilayer TiC-based coating with the upper DLC layer, in addition to high tribological properties, was characterized by the lowest corrosion current density (12 μA/cm2).

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In vitro bioactivity study of TiCaPCO(N) and Ag‐doped TiCaPCO(N) films in simulated body fluid

Cited by 10 publications

References 67 publications

In Vitro Biological Characterization of Silver-Doped Anodic Oxide Coating on Titanium

In Vitro Biological Characterization of Silver-Doped Anodic Oxide Coating on Titanium

Characteristics and in vitro response of thin hydroxyapatite–titania films produced by plasma electrolytic oxidation of Ti alloys in electrolytes with particle additions

Two-Layer Nanocomposite TiC-Based Coatings Produced by a Combination of Pulsed Cathodic Arc Evaporation and Vacuum Electro-Spark Alloying

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