In vitro antioxidant activity of rice protein affected by alkaline degree and gastrointestinal protease digestion

Abstract

The present study indicates that antioxidant capacity of RP could be more readily depressed by strict alkali degree and affected by gastrointestinal proteases. Results suggest that alkali extraction is a vital process to regulate the antioxidant activity of RP through modifying the compositions of amino acids, which are dependent on alkali magnitude. © 2016 Society of Chemical Industry.

Rice protein reduces DNA damage by activating the p53 pathway and stimulating endogenous antioxidant response in growing and adult rats

“…Rice protein can exert antioxidant activity to reduce oxidative stress. 15,16,[24][25][26] The present study demonstrated that rice protein could reduce ROS-derived DNA damage, which was attributable to the stimulation of an antioxidative response to rice protein intake. More significantly, results indicated that the effect of rice protein on reducing DNA damage was attributable to the activation and the up-regulation of the ATM-Chk2-p53 pathway in growing and adult rats.…”

“…Rice protein can exert antioxidant activity to reduce oxidative stress . The present study demonstrated that rice protein could reduce ROS‐derived DNA damage, which was attributable to the stimulation of an antioxidative response to rice protein intake.…”

“…Rice protein has its own protein components, including albumin (water soluble), globulin (salt soluble), glutelin (alkali / acid soluble), and prolamin (alcohol soluble), in which glutelin and prolamin are major storage proteins . Rice and rice protein have numerous physiological functions, in which some studies have clearly indicated an association between rice protein consumption and a reduced risk of oxidative stress . Higher sulfur‐containing amino acid (SAAs), hydrophobic amino acid (HAAs), and arginine content in rice protein might contribute to physiological functions, such as antioxidant activity or hypolipidemic action .…”

“…[15][16][17] Rice and rice protein have numerous physiological functions, [18][19][20][21][22][23] in which some studies have clearly indicated an association between rice protein consumption and a reduced risk of oxidative stress. 15,16,[24][25][26] Higher sulfur-containing amino acid (SAAs), hydrophobic amino acid (HAAs), and arginine content in rice protein might contribute to physiological functions, such as antioxidant activity or hypolipidemic action. [15][16][17]27 Significantly, new evidence has emerged to show the antioxidant mechanism employed by the rice protein, which operates through the activation of nuclear factor erythroid 2 (NF-E2)-related factor 2 (Nrf2).…”

l‐Methionine activates Nrf2‐ARE pathway to induce endogenous antioxidant activity for depressing ROS‐derived oxidative stress in growing rats

“…It is suggested that sulfur‐containing amino acid plays a key role in antioxidant defense . With this in view, the effect of l ‐ methionine on inducing the endogenous antioxidant response was focused on in this study.…”