<i>In vitro</i> and <i>in vivo</i> evaluation of a desonide gel-cream photostabilized with benzophenone-3

Rosa, Philippe; Santos, Juliana dos; Lehmen, Tassia; Wéber, Júlia; Flôres, Fabíola Niederauer; Silva, Cristiane de Bona da; Oliveira, Sara Marchesan; Brusco, Indiara; Milani, Gessica Brum; Adams, Andréa Inês Horn

doi:10.3109/03639045.2015.1022554

Cited by 4 publications

(1 citation statement)

References 42 publications

(42 reference statements)

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“…Considered as a relatively new semisolid form, gel-creams are oil-in-water systems containing a polymeric solution as thickened aqueous external phase (Rosa et al, 2016). Gelcreams have arisen as an alternative in order to diminish the amount of lipids in the formulation in the presence of lipophilic active substances and when patient exhibits greasy skin.…”

Section: Formulations Vehiclesmentioning

confidence: 99%

Profile of depigmenting cosmetics and dermatological products on the market

Rotava

Favero

Garcia

et al. 2020

Rev. Ciênc. Farm. Básica Apl.

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The skin is the largest and most exposed organ of the human body, therefore subject to diseases and alteration of its appearance. Among these alterations, the cutaneous hyperchromia may be cited. Currently, the market offers numerous products with depigmenting action to the treatment of such disorders. The aim of this work was to analyze depigmenting products commercialized in establishments in the city of Bento Gonçalves (RS, Brazil) and websites of cosmetic companies. It was found 45 products with depigmenting action and, from these, 59 different active agents were identified. The main active compounds found were kojic acid, arbutin, ascorbic acid, hydroquinone and glycolic acid. Another observed data was that in 78% of the studied products the active substances were being used in combination. The most used vehicles were also studied as a reference to the use of sunscreen in the treatment of cutaneous hyperchromia. The present work had identified in the market a variety of products with depigmentation action and, because of this, it aims to serve as a reference to the healthcare professionals, especially at the prescribing moment, looking for the best results, with regards to treatment efficiency and safety.

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Section: Formulations Vehiclesmentioning

confidence: 99%