Abstract:MicroRNAs (miRNAs) are key regulators of cell and tissue development. However, spatial resolution of miRNA heterogeneity and accumulation patterns in vivo remains uncharted. Next‐generation sequencing methods assay miRNA abundance in tissues, yet these analyses do not provide spatial resolution. A method to assay miRNA expression at single‐cell resolution in vivo should clarify the cell‐autonomous functions of miRNAs, their roles in influencing the cellular microenvironment, and their perdurance and turnover r… Show more
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