In silicoscreening for oligopeptides useful as capture and reporting probes for interleukin-6 biosensing

Abstract

In silico design by docking and molecular dynamics of short peptides that can selectively recognize IL-6 for biosensing purposes.

Enhanced sensitivity in electrochemical detection of ochratoxin A within food samples using ferrocene- and aptamer-tethered gold nanoparticles on disposable electrodes

“…In silico simulations, by molecular docking and molecular dynamics, can provide several useful information on the binding site, the interaction energies and study degradation kinetics, [56][57][58][59][60] especially if coupled to experimental techniques. 57,61 Docking results.…”

Detection of SARS-CoV-2 N protein using AgNPs-modified aligned silicon nanowires BioSERS chip

“…Aptamer-based biosensors employ aptamers as recognition elements linked to a physical signal transducer, translating the binding interaction between the aptamer and its target into a detectable signal, thereby facilitating precise and selective identication of particular analytes. 12,13 The use of aptamers, which are single-stranded DNA or RNA oligonucleotides, in biosensing as specic receptors for quick screening of disease biomarkers has garnered signicant interest. To replace antibodies, which are oen costly and subject to degradation, aptamer-based biosensing devices are used.…”