“…18,21,28 In diagnostic and theranostic research, many luminescent probes have been reported to sense a variety of biological, chemical and environmental analytes but there are still challenges with tuning the luminescence properties of these probes. 29,30 Similarly, the roles of thiazetidines, quinolines and fused imidazoquinolines towards anti-cancer and anti-microbial properties were explored through computational methods, 31,32 but there are limitations in synthesizing these structures; Click chemistry can be employed to overcome these drawbacks. Although some issues exist with the reactivity of Click reactants, efforts to overcome these are underway, particularly for applications like direct conjugation, 19,33 induced drug release and delivery of gaseous signalling molecules.…”