Helicobacter pylori and extragastric diseases

Abstract

Many studies have been performed in the last year concerning the potential role of Helicobacter pylori in different extragastric diseases, reinforcing the idea that specific microorganisms may cause diseases even far from the primary site of infection. While the role of H. pylori on idiopathic thrombocytopenic purpura, sideropenic anemia, and vitamin B12 deficiency has been well established, there is a growing interest in other conditions, such as cardiovascular, neurologic, dermatologic, obstetric, immunologic, and metabolic diseases. Concerning neurologic diseases, there is a great interest in cognitive impairment and neurodegeneration. The aim of this review was to summarize the results of the most relevant studies published over the last year on this fascinating topic.

Helicobacter pylori infection and increased diabetes prevalence were the risks of colorectal adenoma: a systematic review and meta-analysis

“…(Figure 3 B H. pylori infection is the main cause of chronic gastritis and peptic ulcer disease and is the main carcinogen for gastric malignancy disease [56]. In the extragastric system, H. pylori infection has also been reported to be related to inflammatory bowel disease, colorectal neoplasms, and cardiovascular disease; to contribute to insulin resistance, associated metabolic syndrome, diabetes, autoimmune disease, and kidney disease; and to be associated with neurodegenerative disease, respiratory disease and hematologic disease [57,58]. In these studies, most scientists addressed the topic of H.…”

Helicobacter pylori infection and increased diabetes prevalence were the risks of colorectal adenoma: a systematic review and meta-analysis

“…(Figure 3 B H. pylori infection is the main cause of chronic gastritis and peptic ulcer disease and is the main carcinogen for gastric malignancy disease [56]. In the extragastric system, H. pylori infection has also been reported to be related to inflammatory bowel disease, colorectal neoplasms, and cardiovascular disease; to contribute to insulin resistance, associated metabolic syndrome, diabetes, autoimmune disease, and kidney disease; and to be associated with neurodegenerative disease, respiratory disease and hematologic disease [57,58]. In these studies, most scientists addressed the topic of H. pylori infection related to colorectal neoplasm formation [3,6,8,9,19,.…”

Helicobacter pylori infection and increased diabetes prevalence were the risks of colorectal adenoma: a systematic review and meta-analysis

“…(Figure 3 H. pylori infection is the main cause of chronic gastritis and peptic ulcer disease and is the main carcinogen for gastric malignancy disease [56]. In the extragastric system, H. pylori infection has also been reported to be related to inflammatory bowel disease, colorectal neoplasms, and cardiovascular disease; to contribute to insulin resistance, associated metabolic syndrome, diabetes, autoimmune disease, and kidney disease; and to be associated with neurodegenerative disease, respiratory disease and hematologic disease [57,58]. In these studies, most scientists addressed the topic of H.…”