FGFR1/2/3‐rearranged carcinoma of the head and neck: expanded histological spectrum crossing path with high‐risk HPV in the sinonasal tract
Ying‐Hsia Chu,
Kerry Mullaney,
Sara E DiNapoli
et al.
Abstract:AimsOncogenic FGFR1/2/3 rearrangements are found in various cancers. Reported cases in head and neck (HN) are mainly squamous cell carcinomas (SCCs) with FGFR3::TACC3 fusions, a subset of which also harbour high‐risk human papillomavirus (HPV). However, the knowledge of the clinicopathological spectrum of FGFR‐rearranged head and neck carcinomas (FHNC) is limited.Methods and resultsA retrospective MSK‐fusion clinical sequencing cohort 2016–23 was searched to identify malignant tumours in the HN region harbouri… Show more
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