<i>Effect of Increased Jugular Pressure on Cerebral Hemodynamics</i>

Moyer, John H.; Miller, Sam I.; Snyder, Harvey

doi:10.1152/jappl.1954.7.3.245

Cited by 24 publications

(9 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It is possible, however, that cerebral blood flow is maintained during the rise in venous pressure, as it is in the adult at venous pressures up to 300 mm c.s.f. (Moyer, Miller & Snyder, 1954;Kety, Shenkin & Schmidt, 1948). Such a mechanism is likely in the new-born, since otherwise syncope would be expected to occur during crying.…”

Section: Pa)mentioning

confidence: 99%

An estimation of intracranial blood flow in the new‐born infant.

Cross¹,

Dear²,

Hathorn³

et al. 1979

The Journal of Physiology

View full text Add to dashboard Cite

4. The jugular veins in the baby's neck are occluded by finger pressure and there follows an increase in skull volume, which is rapid at first, but which decreases exponentially as venous drainage diverts to non-occluded channels such as the vertebral venous plexus. At the instant of jugular occlusion the rate of skull volume increase is representative of the rate of flow in the jugular vessels prior to occlusion, and so provides an index of the relative magnitude of the intracranial blood flow. The method thus allows changes in intracranial blood flow to be followed. When occlusion is released cranial volume decreases, initially rapidly, but slowing exponentially as resting volume is regained.5. A theoretical model of the events occurring during the inflow and outflow phases has been developed, and a formula derived which allows an estimation to be made of the flow of blood through uncompressed channels. The measured value of jugular blood flow can then be augmented to an estimate of total intracranial flow.6. The mean cerebral blood flow of sixteen normal babies was estimated to be 40 ml. 100 g-1. min-' (S.D. = + 11t63).

show abstract

Section: Pa)mentioning

confidence: 99%

An estimation of intracranial blood flow in the new‐born infant.

Cross¹,

Dear²,

Hathorn³

et al. 1979

The Journal of Physiology

View full text Add to dashboard Cite

show abstract

“…[200], who compressed the jugular veins of patients with heart failure; Chai et al . [201], who performed jugular vein ligation in a swine model; and Bateman [202], who investigated idiopathic intracranial hypertension associated with venous outflow stenosis.…”

Section: Introductionmentioning

confidence: 99%

Venous hemodynamics in neurological disorders: an analytical review with hydrodynamic analysis

Beggs

2013

BMC Med

107

102

View full text Add to dashboard Cite

Venous abnormalities contribute to the pathophysiology of several neurological conditions. This paper reviews the literature regarding venous abnormalities in multiple sclerosis (MS), leukoaraiosis, and normal-pressure hydrocephalus (NPH). The review is supplemented with hydrodynamic analysis to assess the effects on cerebrospinal fluid (CSF) dynamics and cerebral blood flow (CBF) of venous hypertension in general, and chronic cerebrospinal venous insufficiency (CCSVI) in particular.CCSVI-like venous anomalies seem unlikely to account for reduced CBF in patients with MS, thus other mechanisms must be at work, which increase the hydraulic resistance of the cerebral vascular bed in MS. Similarly, hydrodynamic changes appear to be responsible for reduced CBF in leukoaraiosis. The hydrodynamic properties of the periventricular veins make these vessels particularly vulnerable to ischemia and plaque formation.Venous hypertension in the dural sinuses can alter intracranial compliance. Consequently, venous hypertension may change the CSF dynamics, affecting the intracranial windkessel mechanism. MS and NPH appear to share some similar characteristics, with both conditions exhibiting increased CSF pulsatility in the aqueduct of Sylvius.CCSVI appears to be a real phenomenon associated with MS, which causes venous hypertension in the dural sinuses. However, the role of CCSVI in the pathophysiology of MS remains unclear.

show abstract

“…Hg. Cerebral blood flow was not altered by this procedure (10). This indicates that cerebral blood flow is not reduced by increases in venous pressure within the limits present in patients with congestive heart failure.…”

Section: Commentsmentioning

confidence: 59%