(E)-1-[4-(Hexyloxy)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one

Abstract

In the title compound, C21H24O3, inter­molecular O—H⋯O and C—H⋯O inter­actions form bifurcated acceptor bonds, generating R 2 1(6) ring motifs. These ring motifs link the mol­ecules into extended chains along [010]. The crystal structure is further stabilized by C—H⋯π inter­actions.

(E)-1-[4-(Hexyloxy)phenyl]-3-(2-hydroxyphenyl)prop-2-en-1-one

“…(2.253 Å) interatomic contact. Similar features were also observed in closely related structures (Razak et al, 2009;Ngaini et al, 2010;Ngaini et al, 2011).…”

“…For a related structure and background to the biological properties of chalcones, see: Ngaini et al (2011). For related structures, see: Razak et al (2009); Ngaini et al (2010).…”

“…Data collection: APEX2 (Bruker, 2009); cell refinement: SAINT (Bruker, 2009); data reduction: SAINT; program(s) used to solve structure: SHELXTL (Sheldrick, 2008); program(s) used to refine structure: SHELXTL; molecular graphics: SHELXTL; software used to prepare material for publication: SHELXTL and PLATON (Spek, 2009 As part of our ongoing studies of the biological activities of chalcone derivatives (Ngaini et al, 2011), the title compound has been synthesised and tested against E. coli ATCC 8739 and showed anti-microbial activity. We now describe its crystal structure.…”

(E)-1-(3-Hydroxyphenyl)-3-[4-(tetradecyloxy)phenyl]prop-2-en-1-one

“…and C1-C6-C7 (123.31 (10)°) angles, respectively. The geometric parameters are consistent to those observed in closely related structures (Razak et al, 2009;Ngaini et al, 2010;Ngaini et al, 2011).…”

(E)-1-(4-Decyloxyphenyl)-3-(2-hydroxyphenyl)prop-2-en-1-one

“…For the biological properties of chalcone derivatives, see: Bhat et al (2005); Xue et al (2004); Won et al (2005); Zhao et al (2005); Satyanarayana et al (2004). For related structures, see: Razak et al (2009); Ngaini et al (2010Ngaini et al ( , 2011. For graph-set theory, see: Bernstein et al (1995).…”