Abstract:Drosophila melanogaster
is a useful model for studying innate immunity that has been used to identify and characterise the role of the Toll pathway and nuclear factor‐κB (NFκB) signalling in both insects and mammals. When flies encounter a pathogen, two pattern recognition pathways, Toll and imd, induce a humoral immune response consisting primarily of antimicrobial peptide production.
Drosophila
also has a cellular immune… Show more
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