2022
DOI: 10.1101/2022.10.19.512518
|View full text |Cite
Preprint
|
Sign up to set email alerts
|

dnaE2expression promotes genetic diversity and bacterial persistence in mycobacterial biofilms

Abstract: The complex cellular architecture and the microenvironments within the biofilm give rise to a population that is both physiologically and genetically heterogenous. Transcriptome analysis of Mycobacterium smegmatis in biofilm culture and its transition phase into planktonic growth was performed to identify the genetic basis of heterogeneity in the biofilm. While there was an increase in the expression of mycobacterial mutasome consisting of dnaE2, imuA and imuB in the biofilm, the mutation burden was less compa… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
0
0

Publication Types

Select...

Relationship

0
0

Authors

Journals

citations
Cited by 0 publications
references
References 62 publications
0
0
0
Order By: Relevance

No citations

Set email alert for when this publication receives citations?